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Noir 40mg/gm (Cream)

Manufactured by: Pharmasia Ltd.

Hydroquinone Similar medicine

Noir is indicated for Chloasma, Melasma, Freckles, Senile lentigines, Hyperpigmentation

Precautions and warnings

Hydroquinone is a skin bleaching agent which may produce unwanted cosmetic effects if not used as directed. The physician should be familiar with the contents of this insert before prescribing or dispensing this medication.Test for skin sensitivity before using by applying a small amount to an unbroken patch of skin to check in 24 hours. Minor redness is not a contraindication, but where there is itching or vesicle formation or excessive inflammatory response, further treatment is not advised. If no bleaching or lightening effect is noted after 2 months of treatment, the medication should be discontinued.Contact with the eyes and lips should be avoided. Hydroquinone should not be applied to cut or abraded skin.

Side-effects

No systemic adverse reactions have been reported. Occasional hypersensitivity (localized contact dermatitis) may occur in which case the medication should be discontinued.

Contraindications

Hydroquinone is contraindicated to patients with prior history of hypersensitivity or allergic reaction to hydroquinone or other ingredients in the preparation.

Mode of actions

Hydroquinone is a topical depigmentating agent used in hyperpigmentation conditions by suppressing melanocyte metabolic processes. It also increases melanin excretion from melanocytes and prevents its production.

Dosage & Administration

Hydroquinone should be applied to the affected area and rubbed in well twice daily or as directed by a physician. Most discolorations begin to lighten after 4 weeks of treatment but it may take longer. After desired bleaching, use only as needed to maintain results of treatment. Hydroquinone bleaching is faster, more dependable and easier if the treated area is protected from ultraviolet light. Therefore, exposure to sunlight should be minimized at the period of treatment. During day, an effective broad-spectrum sunscreen should be used, unnecessary solar exposure should be avoided and protective clothing should be used to prevent repigmentation of treated areas. After reduction of hyperpigmentation, use of sunscreen agents and/or protective clothing should continue.Use in children: Safety and efficacy in paediatric patients below the age of 12 years have not been established.

Pregnancy & Lactation

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks