Rasilez 300mg (Tablet)
Manufactured by: Novartis Farma SpA, Italy
Aliskiren Similar medicine
Rasilez is indicated for
- Hipertensão
Precautions and warnings
ICC grave, depleção de sódio ou depleção de volume. Se a diarréia for severa e persistente, pare de tomá -la. Lactação. Parâmetros a serem monitorados monitoram os níveis séricos de potássio e a função renal regularmente.
Side-effects
- Diarréia
- dispepsia
- gerd
- dor abdominal
- hipotensão
- dor de cabeça
- fadiga
- tontura
- dor nas costas
- tosse
- erupções cutâneas
- hiperuricaemia
- gota
- cálculos renais
- hipercalemia
- diminuições nos níveis de Hb (dose)
- angioedema e sintina. Potencialmente fatal: reações anafiláticas.
Drug Interactions
Juntamente com outros anti -hipertensivos, há um risco aumentado de hipotensão. Inibidores da ECA, antagonistas do receptor da angiotensina II e medicamentos anti-inflamatórios não esteróides aumentam o risco de insuficiência renal aguda. Com os AINEs, o impacto anti -hipertensivo pode ser diminuído. Atorvastatina, itraconazol, cetoconazol e verapamil aumentaram os níveis séricos. As concentrações de furosemida e aliskiren caíram significativamente. Com diuréticos poupadores de potássio, suplementos de potássio ou qualquer outro agente que possa aumentar os níveis séricos de potássio, há um risco aumentado de hipercalemia.
Com inibidores da ECA ou antagonistas do receptor da angiotensina II, há um maior risco de comprometimento renal, hipotensão e hipercalemia. Acentuadamente aumentou a concentração plasmática com ciclosporina, itraconazol e quinidina.
Contraindications
História de Angioedema; Recomenda -se um comprometimento renal significativo em pacientes com diabetes e comprometimento renal (TFG), recomenda -se o uso concomitante de inibidores da ECA ou antagonistas do receptor da angiotensina II.
Mode of actions
O Aliskiren é um inibidor de renina direta não peptídico, ativo, poderoso e específico usado para tratar o HTN. Ele bloqueia a conversão de angiotensinogênio em angiotensina I e, portanto, a síntese subsequente da angiotensina II e aldosterona bloqueando a enzima renina. O tratamento com aliskiren reduz a atividade da renina plasmática e as concentrações de angiotensina I, angiotensina II e aldosterona, diferentemente dos inibidores da ECA e antagonistas dos receptores da angiotensina II, que promovem uma onda compensatória na atividade da renina plasma.
Dosage & Administration
Oral
Hipertensão essencial
Adulto:> 18 anos 150 mg uma vez ao dia, aumentou para 300 mg uma vez ao dia, se necessário.
Idosos: não é necessário ajuste de dose.
INSCRIMENTO HEPÁTICO: Não é necessário ajuste de dose.
Pregnancy & Lactation
Este medicamento não é permitido durante a gravidez. Não use -o se estiver grávida. Pode ser absorvido pela pele e os pulmões causados podem danificar os órgãos do seu filho ainda não nascido e causar deficiências congênitas. Controle eficaz rigoroso da natalidade durante o tratamento e por seis meses depois de interromper este medicamento. Se você engravidar, pare de tomar este medicamento e discuta seu médico imediatamente.
Não há informações específicas sobre se este medicamento passa para o leite materno ou não. Considerando os possíveis riscos para as crianças, a amamentação ao usar este medicamento não é recomendada e pelo menos duas semanas após a última dose. Consulte seu médico antes de amamentar.
Pack Size & Price
7's pack Price : ৳437.5
Similar medicine
Manufactured by: Novartis Farma SpA, Italy
Manufactured by: Novartis Farma SpA, Italy
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There are few similar medicines of Rasilez are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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