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Saflox 500mg (Tablet)

Manufactured by: Salton Pharmaceuticals Ltd.

Ciprofloxacin Similar medicine

Saflox is indicated for

  • Cystic fibrosis
  • Intra-abdominal infections
  • Meningitis
  • Peritonitis
  • Endocarditis
  • Anthrax
  • Otitis media
  • Septicaemia
  • Lower Respiratory Tract Infections
  • Cystitis
  • Gonorrhoea
  • Skin
  • skin structure infections
  • Nosocomial pneumonia
  • Urinary tract infections
  • Enteric fever
  • Bone
  • Joint Infections
  • Biliary tract infections
  • Surgical Prophylaxis
  • Gastroenteritis
  • Q fever
  • Acute Sinusitis
  • Cat scratch disease
  • Spotted fever
  • Typhus
  • Chanroid
  • Brucellosis
  • Typhoid
  • paratyphoid fever
  • Superficial ophthalmic infections
  • Otitis externa

Precautions and warnings

Epilepsy, history of CNS disorders; severe renal or hepatic dysfunction;G6PD deficiency; maintain capable hydration; myasthenia graves, Caution when used in patients with QT prolongation or risk factors for example, bradycardia, pre-present cardiac disease or uncorrected electrolyte disturbances, Discontinue treatment if patients feel tendon pain, inflammation or tear up, Avoid usage in methicillin-resistant staphylococcus aureus (MRSA) infections due to high even of resistance, May impair ability to drive or control machinery, Safety and efficacy have not been habitual in great and lactating women, Not to be used in children.

Side-effects

  • GI disturbances; headache
  • tremor
  • confusion
  • convulsions; rashes; joint pain; phototoxicity. Transient increases in serum creatinine. Haematological
  • hepatic
  • renal disturbances. Vasculitis
  • pseudomembranous colitis
  • tachycardia. Phototoxicity. Potentially Fatal: Anaphylactoid reaction; cardiopulmonary arrest.

Drug Interactions

May increase plasma concentrations of CYP1A2 substrates (for example, clozapine, ropinirole, theophylline),Enhances effect of oral anticoagulants (for example, warfarin) and glibenclamide, Increased toxicity of methotrexate, Plasma concentrations may be increased by probenecid, Reduced absorption along with oral multivitamins and mineral supplements containing power or power cations (for example, Fe, Zn, Ca) and antacids containing Al, Ca or Mg, Concomitant use along with sort IA antiarrhythmics (for example, quinidine, procainamide), class III antiarrhythmics (for example, amiodarone, stall), TCAs, macrocodes and antipsychotics may lead in cumulative effects on QT interval prolongation, Concurrent use along with corticosteroids may increase risk of severe tendon disorders, Increased risk of CNS stimulation along with NSAIDs,Altered serum concentrations of phenytoin,Potentially Fatal: Marked elevation in serum levels of tizanidine which is associated along with potentiated hypotensive and ataraxic effect.

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Contraindications

Hypersensitivity, Not to be used concurrently with tizanidine, Avoid exposure to tough sunlight or sun lamps during treatment.

Mode of actions

Ciprofloxacin promotes breakage of double-marooned DNA in susceptible organisms and inhibits DNA gyrates, which is essential in reproduction of bacterial DNA.

Dosage & Administration

Adult Dose: For oral dosage & suspension: Urinary Tract infection: Acute uncomplicated: 250 mg twice daily for 3 days; Mild/Moderate: 250 mg twice daily for 7 to 14 days; Severe/Complicated: 500 mg twice daily for 7 to 14 days;

Chronic Bacterial Prostitis : 500 mg twice daily for 28 days;

Lower Respiratory Tract infection: Mild/Moderate: 500 mg twice daily for 7 to 14 days, Severe/Complicated : 750 mg twice daily for 7 to 14 days;

Acute Sinusitis : 500 mg twice daily for 10 days; Skin and Skin Structure infection: Mild/Moderate : 500 mg twice daily for 7 to 14 days, Severe/Complicated : 750 mg twice daily for 7 to 14 days,

Bone and joint infection: Mild/Moderate 500 mg twice daily for 4 to 6 weeks, Severe/Complicated : 750 mg twice daily for 4 to 6 weeks,

Intra Abdominal Infection: 500 mg twice daily for 7 to 14 days, Infectious Diarrhea: Mild/Moderate/Severe: 500 mg twice daily for 5 to 7 days, Typhoid Fever : 500 mg twice daily for 10 days,

Urethral & Cervical Gonococcal Infections: Uncomplicated: 250 mg Single dose.

For IV infusion : Urinary Tract Infection: Mild to Moderate: 200 mg 12 hourly for 7-14 days;Severe or Complicated: 400 mg 12 hourly for 7-14 days;

Lower Respiratory Tract infection: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days; Nosocomial Pneumonia: Mild/Moderate/Severe: 400 mg 8 hourly for 10-14 days;

Skin and Skin Structure: Mild to Moderate: 400 mg 12 hourly for 7-14 days; Severe or Complicated: 400 mg 8 hourly for 7-14 days; Bone and Joint Infection: Mild to Moderate: 400 mg 12 hourly for more than 4-6 weeks; Severe/Comlicated: 400 mg 8 hourly for more than 4-6weeks;

Intra abdominal (Acute abdomen): Complicated: 400 mg 12 hourly for 7-14 days; Acute Sinusitis: Mild/Moderate: 400 mg 12 hourly for10 days:
Chronic Bacterial Prostatitis: Mild/Moderate: 400 mg 12 hourly for 28 Days.

Children and adolescents: RTI & GI infections: Neonate-15mg/kg twice daily, Child (1 month -18 years)-20mg/kg (max 750 mg) twice daily;
UTI: Neonate-10 mg/kg twice daily, Child (1 month -18 years)-10mg/kg (max 750 mg) twice daily;

Pseudomonal lower respiratory tract infection in cystic fibrosis: Child (1 month -18 years) - 20mg/kg (max 750 mg) twice daily; Anthrax (treatment & post exposure prophylaxis): Child (1 month -18 years) - 20mg/kg (max 750 mg) twice daily.

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.

Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.

This medicine passes into breast milk. Talk to your doctor before breastfeeding.

Pack Size & Price

30's pack Price : ৳367.2

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There are some similar medicines of Saflox are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.

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Indicated for Cystic fibrosis, Intra-abdominal infections, Meningitis, Peritonitis, Endocarditis, Anthrax, Otitis media, Septicaemia, Lower Respiratory Tract Infections, Cystitis, Gonorrhoea, Skin and skin structure infections, Nosocomial pneumonia, Urinary tract infections, Enteric fever, Bone and Joint Infections, Biliary tract infections, Surgical Prophylaxis, Gastroenteritis, Q fever, Acute Sinusitis, Cat scratch disease, Spotted fever, Typhus, Chanroid, Brucellosis, Typhoid and paratyphoid fever, Superficial ophthalmic infections, Otitis externa

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Indicated for Pneumonia, Cystic fibrosis, Bacterial septicemia, Meningitis, Peritonitis, Skin and Skin-Structure Infections, Endometritis, Pelvic cellulitis, Respiratory tract infections, Urinary tract infections, Febrile neutropenia, Melioidosis, Bone and Joint Infections, G ynecologic Infections, Biliary tract infections, Endophthalmitis

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Ciprofloxacin

Indicated for Cystic fibrosis, Intra-abdominal infections, Meningitis, Peritonitis, Endocarditis, Anthrax, Otitis media, Septicaemia, Lower Respiratory Tract Infections, Cystitis, Gonorrhoea, Skin and skin structure infections, Nosocomial pneumonia, Urinary tract infections, Enteric fever, Bone and Joint Infections, Biliary tract infections, Surgical Prophylaxis, Gastroenteritis, Q fever, Acute Sinusitis, Cat scratch disease, Spotted fever, Typhus, Chanroid, Brucellosis, Typhoid and paratyphoid fever, Superficial ophthalmic infections, Otitis externa

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Ceftazidime

Indicated for Pneumonia, Cystic fibrosis, Bacterial septicemia, Meningitis, Peritonitis, Skin and Skin-Structure Infections, Endometritis, Pelvic cellulitis, Respiratory tract infections, Urinary tract infections, Febrile neutropenia, Melioidosis, Bone and Joint Infections, G ynecologic Infections, Biliary tract infections, Endophthalmitis

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Ciprofloxacin

Indicated for Cystic fibrosis, Intra-abdominal infections, Meningitis, Peritonitis, Endocarditis, Anthrax, Otitis media, Septicaemia, Lower Respiratory Tract Infections, Cystitis, Gonorrhoea, Skin and skin structure infections, Nosocomial pneumonia, Urinary tract infections, Enteric fever, Bone and Joint Infections, Biliary tract infections, Surgical Prophylaxis, Gastroenteritis, Q fever, Acute Sinusitis, Cat scratch disease, Spotted fever, Typhus, Chanroid, Brucellosis, Typhoid and paratyphoid fever, Superficial ophthalmic infections, Otitis externa

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