Discover More

Topics | Healthy living | Amazing Healthy living secrets must steal ASAP

Roxadex 5mg/ml (Injection)

Manufactured by: Nuvista Pharma Ltd

Dexamethasone Sodium Phosphate Similar medicine

Roxadex is indicated for

  • Ulcerative colitis
  • Rheumatoid arthritis
  • Multiple sclerosis
  • Nausea
  • vomiting
  • Multiple myeloma
  • Cerebral oedema
  • Shock
  • Inflammatory joint diseases
  • Idiopathic thrombocytopenic purpura
  • Dental surgery
  • Allergic anaphylactic shock
  • Brain tumors
  • Status asthmaticus

Precautions and warnings

This product, like many other steroid formulations, is sensitive to wake, Therefore, it should not be autoclaved when it is desirable to fi the outside of the vial.


Following prolonged therapy, withdrawal of corticosteroids may lead in symptoms of the corticosteroid withdrawal syndrome including fever, myalgia, arthralgia, and malaise, This may come in patients equal without tell of adrenal insufficiency.


There Is an increased effect of corticosteroids in patients with hypothyroidism and in those with cirrhosis.


Corticosteroids Should be used cautiously in patients with ocular herpes simplex for reverence of corneal perforation.


The Last workable dose of corticosteroid should be used to control the condition under treatment, and when reduction in dosage is possible, the reduction must be gentle.


Psychic Derangements may seem when corticosteroids are used, ranging from euphoria, insomnia, mood swings, personality changes, and severe depression to plainspoken psychotic manifestations, Also, present emotional instability or psychotic tendencies may be angry by corticosteroids.


Aspirin Should be used cautiously in conjunction with corticosteroids in hypoprothrombinemia.


Steroids Should be used with admonish in nonspecific ulcerative colitis, if there is a probability of impending perforation, abscess, or other pyogenic infection, also in diverticulitis, hot intestinal anastomoses, active or latent peptic ulcer, renal insufficiency, hypertension, osteoporosis, and myasthenia gravis.


When Extensive doses are apt, some authorities suggest that antacids be administered between meals to help to prevent peptic ulcer.


Growth And development of infants and children on prolonged corticosteroid therapy should be carefully followed.


Steroids May increase or decrease motility and list of spermatozoa in some patients.


Phenytoin, Phenobarbital, ephedrine, and rifampin may raise the metabolic clearance of corticosteroids resulting in decreased blood levels and mitigated physical activity, thus requiring adjustment in corticosteroid dosage, These interactions may interfere with dexamethasone suppression tests which should be interpreted with months during administration of these drugs.


When Corticosteroids are administered concomitantly with potassium-depleting diuretics, patients should be determined closely for development of hypokalemia.


Intra-articulary Injection of a corticosteroid may raise systemic as well as local effects.

Side-effects

  • Fluid
  • electrolyte disturbances: Sodium retention Fluid retention Congestive heart failure in susceptible patients Potassium loss Hypokalemic alkalosis Hypertension Musculoskeletal: Muscle weakness Steroid myopathy Loss of muscle mass Osteoporosis Pathologic fracture of long bones Vertebral compression fractures Aseptic necrosis of femoral
  • humeral heads Tendon rupture Gastrointestinal: Peptic ulcer with possible subsequent perforation
  • hemorrhage Perforation of the small
  • large bowel
  • particularly in patients with inflammatory bowel disease Pancreatitis Abdominal distention Ulcerative esophagitis Dermatologic: Impaired wound healing Thin fragile skin Petechiae
  • ecchymoses Erythema Increased sweating May suppress reactions to skin tests Burning or tingling
  • especially in the perineal area (after IV injection) Other cutaneous reactions
  • such as allergic dermatitis
  • urticaria
  • angioneurotic edema Neurologic: Convulsions Increased intracranial pressure with papilledema (pseudotumor cerebri) usually after treatment Vertigo Headache Psychic disturbances Endocrine: Menstrual irregularities Development of cushingoid state Suppression of growth in children Secondary adrenocortical
  • pituitary unresponsiveness
  • particularly in times of stress
  • as in trauma
  • surgery
  • or illness Decreased carbohydrate tolerance Manifestations of latent diabetes mellitus Increased requirements for insulin or oral hypoglycemic agents in diabetics Hirsutism Ophthalmic: Posterior subcapsular cataracts Increased intraocular pressure Glaucoma Exophthalmos Metabolic: Negative nitrogen balance due to protein catabolism Cardiovascular: Myocardial rupture following recent myocardial infarction. Other: Anaphylactoid or hypersensitivity reactions Thromboembolism Weight gain Increased appetite Nausea Malaise Hiccups The following additional adverse reactions are related to parenteral corticosteroid therapy: Rare instances of blindness associated with intralesional therapy around the face
  • head Hyperpigmentation or hypopigmentation Subcutaneous
  • cutaneous atrophy Sterile abscess Post-injection flare (following intra-articular use) Charcot-like arthropathy

Drug Interactions

Increased risk of hypokalemia when used concurrently with potassium-depleting drugs such as amphotericin B and curl diuretics, Reduces efficacy of isoniazid, salicylate, vaccines and toxoids, Increased activity of dexamethasone and cyclosporin when used unneurotic, Concurrent use with aspirin or ethanol may head to increased GI lateral effects.

Potentially Fatal: Reduced efficacy in combination with ephedrine, cholestyearamine, phenytoin, phenobarbital and rifampicin.

Contraindications

Systemic fungal infections . Hypersensitivity to any component of this product, including sulfites

Mode of actions

Dexamethasone is a celluloid glucocorticoid which decreases inflammation by inhibiting the migration of leukocytes and reversal of increased capillary permeability, It suppresses normal immune response.

Dosage & Administration

Dexamethasone sodium phosphate injection, – For intravenous, intramuscular, intra-articular, intralesional, and soft tissue injection.
Dexamethasone can be given parenterally at doses of 0.5-20 mg daily, either as a single IV/IM injection or by IV infusion.

Child: 200-500 mcg/kg daily.
Cerebral oedema: 10 mg IV initially, then 4 mg IM every 6 hours as required for 2-10 days. Large IV doses should be given slowly to reduce the possibility of cardiovascular collapse.
Shock: By intravenous or intramascular injection or infusion 2-6 mg/kg, repeated if necessary after 2-6 hours. The total daily intake of Dexamethasone, even in acute conditions should not exceed 80 mg except in certain very special circumstances.

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.

Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.

This medicine passes into breast milk. Talk to your doctor before breastfeeding.

Pack Size & Price

10 amps pack Price : ৳290.2

Similar medicine

Dexagen 5 mg/ml (Injection)

Manufactured by: General Pharmaceuticals Ltd.

Dexamin 5mg/ml (Injection)

Manufactured by: Jayson Pharmaceuticals Ltd.

Metadaxan 5 mg/ml (Injection)

Manufactured by: Incepta Pharmaceuticals Ltd.

Dexam 5mg/ml (Injection)

Manufactured by: Medimet Pharmaceuticals Ltd.

Gludex IM/IV 5mg/ml (Injection)

Manufactured by: Kemiko Pharmaceuticals Ltd.

Dextason 5mg/ml (Injection)

Manufactured by: Ziska Pharmaceuticals Ltd.

Click here to see 13 more similar medicines

There are some similar medicines of Roxadex are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.

Are you looking medicine for Ulcerative colitis ?

5 Aminosalicylic Acid

Indicated for Ulcerative colitis, Ulcerative proctitis, Crohn's Disease.

List of medicines using 5 Aminosalicylic Acid

Betamethasone

Indicated for Ulcerative colitis, Rheumatoid arthritis, Ankylosing spondylitis, Lichen planus, Psoriasis, Asthma, Eczema, Contact dermatitis, Multiple sclerosis, Drug hypersensitivity reactions, Perennial or seasonal allergic rhinitis, Serum sickness, Transfusion reactions, Severe erythema multiforme (Stevens-Johnson syndrome), Leukemias, Lymphomas, Acute gouty arthritis, Acute rheumatic carditis, Psoriatic arthritis, Including juvenile rheumatoid arthritis, Dermatomyositis, Polymyositis, Systemic lupus erythematosus, Psoriatic plaques, Allergic and inflammatory disorders, Congenital adrenal hyperplasia

List of medicines using Betamethasone
6 more generic are used for Ulcerative colitis

Are you looking medicine for Rheumatoid arthritis ?

Betamethasone

Indicated for Ulcerative colitis, Rheumatoid arthritis, Ankylosing spondylitis, Lichen planus, Psoriasis, Asthma, Eczema, Contact dermatitis, Multiple sclerosis, Drug hypersensitivity reactions, Perennial or seasonal allergic rhinitis, Serum sickness, Transfusion reactions, Severe erythema multiforme (Stevens-Johnson syndrome), Leukemias, Lymphomas, Acute gouty arthritis, Acute rheumatic carditis, Psoriatic arthritis, Including juvenile rheumatoid arthritis, Dermatomyositis, Polymyositis, Systemic lupus erythematosus, Psoriatic plaques, Allergic and inflammatory disorders, Congenital adrenal hyperplasia

List of medicines using Betamethasone

Cyclosporine

Indicated for Ulcerative colitis, Rheumatoid arthritis, Psoriasis, Missed abortion, Nephrotic syndrome , Urticaria, Bone marrow transplantation, Organ transplantation, atopic dermatitis

List of medicines using Cyclosporine
4 more generic are used for Rheumatoid arthritis

Are you looking medicine for Multiple sclerosis ?

Betamethasone

Indicated for Ulcerative colitis, Rheumatoid arthritis, Ankylosing spondylitis, Lichen planus, Psoriasis, Asthma, Eczema, Contact dermatitis, Multiple sclerosis, Drug hypersensitivity reactions, Perennial or seasonal allergic rhinitis, Serum sickness, Transfusion reactions, Severe erythema multiforme (Stevens-Johnson syndrome), Leukemias, Lymphomas, Acute gouty arthritis, Acute rheumatic carditis, Psoriatic arthritis, Including juvenile rheumatoid arthritis, Dermatomyositis, Polymyositis, Systemic lupus erythematosus, Psoriatic plaques, Allergic and inflammatory disorders, Congenital adrenal hyperplasia

List of medicines using Betamethasone

Dexamethasone Sodium Phosphate

Indicated for Ulcerative colitis, Rheumatoid arthritis, Multiple sclerosis, Nausea and vomiting, Multiple myeloma, Cerebral oedema, Shock, Inflammatory joint diseases, Idiopathic thrombocytopenic purpura, Dental surgery, Allergic anaphylactic shock, Brain tumors, Status asthmaticus

List of medicines using Dexamethasone Sodium Phosphate
2 more generic are used for Multiple sclerosis

Are you looking medicine for Nausea and vomiting ?

Dexamethasone Sodium Phosphate

Indicated for Ulcerative colitis, Rheumatoid arthritis, Multiple sclerosis, Nausea and vomiting, Multiple myeloma, Cerebral oedema, Shock, Inflammatory joint diseases, Idiopathic thrombocytopenic purpura, Dental surgery, Allergic anaphylactic shock, Brain tumors, Status asthmaticus

List of medicines using Dexamethasone Sodium Phosphate
1 more generic are used for Nausea and vomiting

Are you looking medicine for Multiple myeloma ?

Dexamethasone Sodium Phosphate

Indicated for Ulcerative colitis, Rheumatoid arthritis, Multiple sclerosis, Nausea and vomiting, Multiple myeloma, Cerebral oedema, Shock, Inflammatory joint diseases, Idiopathic thrombocytopenic purpura, Dental surgery, Allergic anaphylactic shock, Brain tumors, Status asthmaticus

List of medicines using Dexamethasone Sodium Phosphate
1 more generic are used for Multiple myeloma

Click here to see more indication similarities

Advertise

You May Like

Advertise