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Sentix 0.5mg (Tablet)

Manufactured by: Eskayef Bangladesh Ltd.

Flupenthixol Similar medicine

Sentix is indicated for

  • Depression
  • Schizophrenia
  • Psychoses

Precautions and warnings

Patients with convulsive disorders; advanced hepatic, renal, CV or resp disease; tasks requiring mental alertness; elderly (especially with dementia), and debilitated patients; neuroleptics with sedative effect must be withdrawn gradually; history of angle-closure glaucoma; urinary retention; prostatic hyperplasia; breast cancer, prolactin dependent tumours; parkinsonism; myasthenia gravis; pregnancy; Avoid direct sunlight.

Side-effects

  • Rigidity
  • tremors
  • restlessness
  • tardive dyskinesia
  • insomnia
  • dryness of mouth
  • wt gain
  • sexual dysfunction
  • galactorrhoea
  • menstrual disturbances. Potentially Fatal: Neuroleptic malignant syndrome (hyperthermia
  • hypertonicity of skeletal muscles
  • unconsciousness
  • autonomic nervous system instability).

Drug Interactions

May potentiate the adverse effects of drugs with antimuscarinic effects e.g. TCAs. Reduced efficacy of levodopa. Increases adverse extrapyramidal symptoms with dopamine antagonists (metoclopramide and prochlorperazine).
Potentially Fatal: Potentiates CNS effects of alcohol, general anaesthetics, hypnotics, anxiolytics and opioids. Blocks antihypertensive effect of guanethidine.

Contraindications

Hypersensitivity. Extremely excitable and overactive patients; mania; porphyria; coma; preexisting CNS depression; bone-marrow supression; phaeochromocytoma. Lactation.

Mode of actions

Flupentixol is a thioxanthene antipsychotic that inhibits dopamine-mediated effects by blocking postsynaptic dopamine receptors in the CNS.

Dosage & Administration

Adult: PO Psychoses Initial: 3-9 mg twice daily. Max: 18 mg/day. Depression Initial: 1 mg/day, increase to 2 mg/day after 1 wk, then to 3 mg/day. Max: 3 mg/day.

IM Psychoses As decanoate: Initial: 20 mg as a test dose. After at least 7 days and depending on response: Subsequent doses of 20-40 mg may be given 2-4 wkly. Usual maintenance: 50 mg 4 wkly to 300 mg 2 wkly, up to 400 mg/wk in severe cases.

Pregnancy & Lactation

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Pack Size & Price

50's pack Price : ৳150

Similar medicine

Sentix 1mg (Tablet)

Manufactured by: Eskayef Bangladesh Ltd.

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There are some similar medicines of Sentix are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.

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