Eskayef Bangladesh Ltd.
Sentix is indicated for
Precautions and warnings
Patients with violent disorders; advanced hepatic, renal, CV or rest disease; tasks requiring knowledge alertness; senior (especially with dementia), and debilitated patients; neuroleptics with depressant effect must be recluse gradually; history of fish-cloture glaucoma; urinary retention; prostatic hyperplasia; breast cancer, prolactin dependent tumors; Parkinsonism; myasthenia graves; pregnancy; Avoid honorable sunlight.
- tardive dyskinesia
- dryness of mouth
- wt gain
- sexual dysfunction
- menstrual disturbances.
Potentially Fatal: Neuroleptic malignant syndrome (hyperthermia
- hypertonicity of skeletal muscles
- autonomic nervous system instability).
May potentiate the unfavorable effects of drugs with antimuscarinic effects for example, TCAs, Reduced efficacy of levodopa, Increases inauspicious extrapyearamidal symptoms with dopamine antagonists (metoclopramide and prochlorperazine),Potentially Fatal: Potentiates CNS effects of alcohol, general anesthetics, hypnotics, anxiolytics and opioids, Blocks antihypertensive effect of guanethidine.
Hypersensitivity, Extremely nervous and overactive patients; mania; porphyearia; coma; antecedent CNS depression; bone-marrow suppression; pheochromocytoma, Lactation.
Mode of actions
Flupentixol is a thioxanthene antipsychotic that inhibits dopamine-mediate effects by blocking postsynaptic dopamine receptors in the CNS.
Dosage & Administration
Adult: PO Psychoses Initial: 3-9 mg twice daily. Max: 18 mg/day. Depression Initial: 1 mg/day, increase to 2 mg/day after 1 wk, then to 3 mg/day. Max: 3 mg/day.
IM Psychoses As decanoate: Initial: 20 mg as a test dose. After at least 7 days and depending on response: Subsequent doses of 20-40 mg may be given 2-4 wkly. Usual maintenance: 50 mg 4 wkly to 300 mg 2 wkly, up to 400 mg/wk in severe cases.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price