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Sentix 0.5mg (Tablet)

Manufactured by: Eskayef Bangladesh Ltd.

Flupenthixol Similar medicine

Sentix is indicated for

  • Depression
  • Schizophrenia
  • Psychoses

Precautions and warnings

People with a history of seizures, severe liver, kidney, heart, or lung disease should use caution with this medicine. Extra care is needed for elderly people (especially those with dementia) and those who are physically weak. If you are taking sedative antipsychotics (neuroleptics), they should be stopped gradually, not suddenly. Use with caution if you have or have had angle-closure glaucoma, trouble urinating, an enlarged prostate, breast cancer, prolactin-dependent tumors, Parkinson’s disease, myasthenia gravis, or if you are pregnant. Avoid exposure to direct sunlight while taking this medicine. Also, be careful if you need to do tasks that require you to be mentally alert.

Side-effects

  • Rigidity
  • tremors
  • restlessness
  • tardive dyskinesia
  • insomnia
  • dryness of mouth
  • wt gain
  • sexual dysfunction
  • galactorrhoea
  • menstrual disturbances. Potentially Fatal: Neuroleptic malignant syndrome (hyperthermia
  • hypertonicity of skeletal muscles
  • unconsciousness
  • autonomic nervous system instability).

Drug Interactions

This medicine can increase the side effects of drugs with antimuscarinic properties, such as tricyclic antidepressants (TCAs). It can also make levodopa work less effectively. When taken with dopamine-blocking drugs like metoclopramide and prochlorperazine, it can worsen movement-related side effects.

Serious Risk: Taking this medicine with alcohol, general anesthetics, sleeping pills, anti-anxiety medications, or opioids can dangerously increase their effects on the brain and nervous system. It can also interfere with the blood pressure-lowering effect of guanethidine.

Contraindications

This medication should not be used in people who are very sensitive or overly excitable. It is also not suitable for patients with mania, porphyria, coma, already existing central nervous system (CNS) depression, bone marrow suppression, or phaeochromocytoma. It should also be avoided during breastfeeding.

Mode of actions

Flupentixol is a type of antipsychotic medicine called a thioxanthene. It works by blocking dopamine receptors in the brain, which helps reduce the effects of dopamine and manage symptoms of mental health conditions.

Dosage & Administration

Adult: PO Psychoses Initial: 3-9 mg twice daily. Max: 18 mg/day. Depression Initial: 1 mg/day, increase to 2 mg/day after 1 wk, then to 3 mg/day. Max: 3 mg/day.

IM Psychoses As decanoate: Initial: 20 mg as a test dose. After at least 7 days and depending on response: Subsequent doses of 20-40 mg may be given 2-4 wkly. Usual maintenance: 50 mg 4 wkly to 300 mg 2 wkly, up to 400 mg/wk in severe cases.

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.

Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.

This medicine passes into breast milk. Talk to your doctor before breastfeeding.

Pack Size & Price

50's pack Price : ৳150

Similar medicine

Sentix 0.5mg (Tablet)

Manufactured by: Eskayef Bangladesh Ltd.

Sentix 1mg (Tablet)

Manufactured by: Eskayef Bangladesh Ltd.

Click here to see more similar medicines

There are few similar medicines of Sentix are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.

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