Neostin-R is indicated for
- H. pylori infection
- Benign gastric
- duodenal ulceration
- Acid aspiration during general anesth
- Prophylaxis during NSAID treatment
- Stress ulceration of upper GI
- Zollinger-Ellison syndrome
Precautions and warnings
Tell your doctor or pharmacist if you have ever had a blood disorder, immune system difficulties, kidney problems, liver problems, lung disorders such asthma, chronic obstructive pulmonary disease-COPD, or other stomach problems before using this drug.
Before treating a stomach ulcer, rule out the possibility of cancer. Renal and hepatic dysfunction. Infants, pregnant women, and mothers who breastfeed their children.
Some symptoms could be warning indications of a more serious ailment. If you have heartburn with lightheadedness, sweating, or dizziness, chest or shoulder pain, especially with shortness of breath, unusual sweating, or unexplained weight loss, seek medical attention right away.
It's possible that this liquid product contains alcohol. If you have diabetes, alcoholism, or liver problems, you should proceed with caution. Inquire with your doctor or pharmacist about the product's safety.
The drug's negative effects, including disorientation, may be more noticeable in older persons.
- dizziness. Rarely hepatitis
Potentially Fatal: Anaphylaxis
- hypersensitivity reactions.
Some products require stomach acid to be adequately absorbed by the body. Because ranitidine lowers stomach acid, it may affect how effectively these medications perform. Atazanavir, dasatinib, delavirdine, and certain azole antifungals like itraconazole, ketoconazole, and pazopanib are among the products affected.
This medicine should not be combined with other medications that contain ranitidine or other H2 blockers like cimetidine, famotidine, or nizatidine.
Mode of actions
Ranitidine decreases stomach acid output by competitively blocking histamine at the H2-receptors of the gastric parietal cells. Pepsin secretion, pentagastrin-stimulated intrinsic factor secretion, and serum gastrin are unaffected.
Dosage & Administration
Adult: PO Benign gastric and duodenal ulceration Initial: 300 mg at bedtime or 150 mg twice daily for 4-8 wk depending on the condition.
For prevention of NSAID-associated ulceration: 150 mg bid.
Eradication of H. pylori infection 300 mg once daily or 150 mg twice daily w/ amoxicillin and metronidazole for 2 wk. May continue w/ ranitidine for a further 2 wk.
GERD 150 mg twice daily or 300 mg at bedtime for up to 8 wk. Severe: 150 mg 4 times/day for 12 wk. Pathological hypersecretory conditions Initial: 150 mg 2-3 times/day, up to 6 g/day if needed.
Acid aspiration during general anesth 150 mg 2 hr before induction of anesth and preferably, an additional dose on the previous evening.
Chronic episodic dyspepsia 150 mg twice daily for up to 6 wk.
Short-term symptomatic dyspepsia 75 mg, up to 4 doses/day if needed. Max: 2 wk of continuous use at each time.
Prophylaxis during NSAID treatment 150 mg twice daily.
IV Pathological hypersecretory conditions Initial: 1 mg/kg/hr, may increase slowly after 4 hr if needed. Stress ulceration of upper GI tract Priming dose: 50 mg via inj, then 125-250 mcg/kg/hr via infusion, then transfer to PO 150 mg twice daily once oral feeding is resumed.
IV/IM Acid aspiration during general anesth 50 mg 45-60 mins before the induction of anasth.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.
Discuss with your doctors and tell them feedback about this medicine.
There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.
Pack Size & Price
The information available on this medicine is only for informational purposes.
Never take Neostin-R without consulting the doctor.
Even, don’t take Neostin-R which has been given by the doctor for other persons
although you guys have the same disease. The above price of Neostin-R may differ
from the actual price in the local market for a variety of reasons, including local taxes and other factors.
This is the only approximate indicative price of this medicine.