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Bivacyn (Spray)

Manufactured by: Novartis (Bangladesh) Ltd.

Bacitracin Zinc + Neomycin Sulphate Topical Similar medicine

Bivacyn is indicated for

  • Bacterial skin infections

Precautions and warnings

Neuromuscular disorders, hearing impaired, extensive skin damage. Avoid application in large quantities and prolonged use. Do not use if tympanic membrane is perforated. Pregnancy and lactation. Liver and renal impairment.

Side-effects

  • Hypersensitivity reactions. Possibility of ototoxicity
  • nephrotoxicity if used in large quantities or on large areas for prolonged use.

Drug Interactions

Bacitracin Zinc: Increased risk of nephrotoxicity when used with other nephrotoxic drugs. May enhance the action of neuromuscular-blocking agents.

Neomycin Sulphate: Additive nephrotoxic and neurotoxic effect w/ other aminoglycosides (e.g. paromomycin), bacitracin, cisplatin, vancomycin, amphotericin B, polymyxin B, colistin and viomycin. Enhanced toxicity w/ potent diuretics (e.g. ethacrynic acid, furosemide). May impair the absorption of other drugs (e.g. phenoxymethylpenicillin, digoxin, methotrexate and some vit). May reduce the efficacy of OCs. May enhance the effect of acarbose. May enhance the effect of non-depolarising muscle relaxants. May antagonise the parasympathomimetic effect of neostigmine and pyridostigmine. May increase the risk of hypocalcaemia in patients receiving bisphosphonates. May alter INR when given w/ anticoagulants. May inactivate oral typhoid vaccine.

Contraindications

Hypersensitivity to aminoglycosides. Pre-existing nerve deafness. Neonates and infants

Mode of actions

Neomycin, an aminoglyoside with antimicrobial spectrum similar to gentamicin, binds to the 30S subunits of the bacterial ribosome, inhibiting protein synthesis and thereby disrupting DNA synthesis. It is active against many gram-negative aerobes and against some strains of staphylococci. Bacitracin, on the other hand, inhibits bacterial cell wall synthesis and is active against many gram-positive bacteria (e.g. staphylococci, streptococci, corynebacteria and clostridia) and some gram-negative species (e.g. Neisseria and Haemophilus influenzae). They are often found in combinations in topical preparations as broad spectrum antibacterial agents.

Dosage & Administration

Adult: Topical: Cream: Apply 3 times/day.
Powder: Apply 2-4 times/day.

Pregnancy & Lactation

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Pack Size & Price

150ml bot Price : ৳244.95

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Neotracin (Powder)

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There are some similar medicines of Bivacyn are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.

Are you looking medicine for Bacterial skin infections ?

Bacitracin Zinc + Neomycin Sulphate + Polymixin B

Indicated for Minor cuts, Scrapes, Burns, Eczematoid dermatitis, Neurodermatitis, Eczema, Anogenital pruritus, Impetigo, Contact dermatitis, Bacterial skin infections

List of medicines using Bacitracin Zinc + Neomycin Sulphate + Polymixin B
5 more generic are used for Bacterial skin infections

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