Novartis (Bangladesh) Ltd.
Ritalin is indicated for
- Hyperactivity disorders
Precautions and warnings
Pregnancy and lactation. History of alcohol or drug abuse. Hypertension and other CV disorders that might be exacerbated by increases in BP or heart rate. Pre-existing psychosis or bipolar disorder; monitor for symptoms of aggression or hostility. History of seizure disorder. Children
- cerebral arteritis
- cerebral occlusion
- changes in BP
- necrotising vasculitis
- pulse changes
- tachycardia; depression
- neuroleptic malignant syndrome (NMS)
- Tourette's syndrome
- toxic psychosis; erythema multiforme
- exfoliative dermatitis
- hair loss
- urticaria; growth retardation; abdominal pain
- weight loss; anaemia
- thrombocytopenic purpura
- thrombocytopenia; abnormal LFTs
- hepatic coma
- increased transaminases; arthralgia
- dyskinesia; blurred vision
- visual accommodation disturbance; cough
- upper respiratory tract infection; accidental injury
- hypersensitivity. Transdermal: Insomnia
- decreased appetite; nausea; tic
- emotional instability; vomiting
- anorexia; nasal congestion
- nasopharyngitis; weight loss.
May reduce effects of antihypertensive agents. Reduced serum level with carbamazepine. Increased serum levels or effects with CYP2D6 inhibitors e.g. chlorpromazine, delavirdine, fluoxetine, miconazole, paroxetine, pergolide, quinidine, quinine, ritonavir, ropinirole. May increase serum levels of phenytoin, TCAs. Possible severe hypertension and tachycardia with sibutramine. CNS depression with alcohol.
Potentially Fatal: Severe toxic reactions with clonidine. Increased risk of hypertensive crisis with MAOIs.
Marked anxiety, tension, agitation; glaucoma; Tourette's syndrome or tics. Known severe structural cardiac abnormalities, cardiomyopathy, serious heart rhythm abnormalities, or other serious cardiac disorders that could increase the risk of sudden death. Extended-release form: Severe hypertension, heart failure, arrhythmia, hyperthyroidism, recent MI or angina.
Mode of actions
Methylphenidate is a central stimulant and indirect-acting sympathomimetic.
Dosage & Administration
Adult: PO Narcolepsy 20-30 mg/day in divided doses. Effective range: 10-60 mg/day.
Pregnancy & Lactation
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Pack Size & Price