Beacon Pharmaceuticals Ltd.
Xalcort is indicated for
- inflammatory disorders
Precautions and warnings
Adrenal suppression and infection, child, adolescents, elderly, history of TB and steroid myopathy, hypertension, recent MI, CHF, liver failure, renal impairment, DM and glaucoma (including family history), osteoporosis, corneal perforation, severe affective disorders, epilepsy, peptic ulcer, hypothyroidism, pregnancy and lactation.
- electrolyte disturbances; susceptible to infection
- impaired healing
- skin atrophy
- myocardial rupture following recent MI
Antacids, ACE inhibitors, acetazolamide, adrenergic neuron blockers, antidiabetics, aspirin, barbiturate, ?-blockers, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs, oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, ?2 sympathomimetics, theophylline, vaccines.
Systemic infection; live virus vaccines in those receiving immunosuppressive doses.
Mode of actions
Deflazacort, derived from prednisolone, is a corticosteroid with mainly glucocorticoid activity. An anti-inflammatory dose of 6 mg deflazacort is equiv to 5 mg prednisolone.
Dosage & Administration
Allergic and inflammatory disorders
Adult: Initially, up to 120 mg daily. Maintenance: 3-18 mg/day.
Child: 0.25-1.5 mg/kg/day given on alternate days.
Hepatic impairment: Dose reductions may be needed.
Pregnancy & Lactation
FDA has not yet classified the drug into a specified pregnancy category.
Pack Size & Price