Precautions and warnings

Tell your doctor about your medical history, especially if you have: certain types of heartbeats, asthma, chronic bronchitis, emphysema, severe heart failure requiring hospitalization, liver disease, kidney disease, blood circulation problems like peripheral vascular disease, serious allergic reactions requiring epinephrine treatment, overactive thyroid disease, a certain type of tumor such as pheochromocytoma, overactive thyroid disease, a certain type of tumor such as pheochromocytoma.

This medication may cause you to feel dizzy, drowsy, or faint. This is most likely to happen within an hour of taking your dose, especially if you're new to carvedilol or if your doctor increases your dose. Avoid driving and other dangerous jobs during these times. Do not drive, operate machinery, or engage in any other activity that requires attentiveness until you are sure you can do so safely. You may become dizzy or sleepy if you consume alcohol or cannabis. Limit your intake of alcoholic beverages. If you use cannabis, talk to your doctor.

Contact lens wearers may experience dry eyes while taking this medicine.

If you have diabetes, this medicine may disguise the rapid, pounding heartbeat that occurs when your blood sugar drops too low. This medication has little effect on other symptoms of low blood sugar, such as dizziness and sweating. This product may also make it more difficult to keep your blood sugar under control. Check your blood sugar as prescribed and inform your doctor of the results. If you have symptoms of high blood sugar, such as increased thirst or urine, call your doctor straight away. Your diabetic medication, exercise routine, or diet may need to be adjusted by your doctor.

Drug Interactions

Along with rifampicin, this medicine is likely to lower serum levels. When taken with Ca channel blockers (such as verapamil and diltiazem), the combination can cause bradycardia and cardiac depression. The insulin-induced hypoglycaemic effect is amplified. Antidiabetic medicines' hypoglycaemic effects may be amplified. Digoxin increases the risk of bradycardia. Reserpine, MAOIs, and clonidine all increase the risk of hypotension and bradycardia. It's possible that ciclosporin levels will rise. When used with ether, cyclopropane, or trichloroethylene, the risk of hypotension and heart failure increases.

Fingolimod is another medicine that may interact with this one.

Contraindications

Severe hepatic impairment, hypersensitivity to the active ingredient, severe chronic heart failure, bronchial asthma or similar bronchospastic diseases. Patients with 2nd or 3rd NYHA class IV cardiac failure

AV block, sick sinus syndrome, cardiogenic shock, or severe bradycardia (unless a permanent pacemaker is in place). A mother who feeds her newborn breast milk.

Mode of actions

Carvedilol is a nonselective adrenergic blocker that promotes vasodilation by inhibiting alpha-1 receptor activation. It works as an antihypertensive by lowering total peripheral resistance and increasing vasodilation.

Dosage & Administration

Hypertension
Adult: Initially, 12.5 mg once daily increased to 25 mg once daily after 2 days. Alternatively, initial dose of 6.25 mg bid increased to 12.5 mg bid after 1-2 wk, increased further if necessary to 50 mg once daily or in divided doses.
Elderly: 12.5 mg once daily.
Angina pectoris
Adult: Initially, 12.5 mg bid increased to 25 mg bid after 2 days.
Heart failure
Adult: Initially, 3.125 mg bid, doubled to 6.25 mg bid after 2 wk if tolerated, then gradually increased to the max dose the patient can tolerate at intervals of not 85 kg: 50 mg bid;

Pregnancy & Lactation

This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.

There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.

Pack Size & Price