Square Pharmaceuticals Ltd.
Alatrol is indicated for Allergic rhinitis, Hay fever, Allergies, Urticaria
Precautions and warnings
Hepatic or renal impairment; elderly; tasks requiring mental alertness eg, driving or operating heavy machinery; pregnancy.
Somnolence, insomnia, malaise, headache, dizziness; GI discomfort, dry mouth, abdominal pain, diarrhoea, nausea, vomiting; occasional hypersensitivity; epistaxis, pharyngitis, bronchospasm.
Additive CNS depression when administered concomitantly w/ other CNS depressants (e.g. sedatives, tranquilisers).
Mode of actions
Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and resp tract.
Dosage & Administration
Adult: 10 mg once daily or 5 mg bid.
Child: 6-23 mth 2.5 mg once daily increased to max of 2.5 mg bid in childn >12 mth; 2-5 yr 5 mg once daily or in 2 divided doses; >6 yr 10 mg once daily or in 2 divided doses.
Elderly: Initially, 5 mg once daily.
Hepatic impairment: Initially, 5 mg once daily.
Adults and children over 6 years: 2 teaspoon once daily or 1 teaspoon twice daily.
Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoon twice daily.
Pregnancy & Lactation
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.