Bexidal is indicated for Allergic conditions

Precautions and warnings

Closed-angle glaucoma; urinary retention, prostatic hyperplasia or pyloroduodenal obstruction; epilepsy. Elderly. Pregnancy. May impair ability to drive or operate machinery.

Side-effects

CNS depression; paradoxical stimulation (high doses, children or elderly); headache, psychomotor impairment; dry mouth, thickened respiratory tract secretions, blurred vision; urinary difficulty or retention, constipation, increased gastric reflux; nausea, vomiting, diarrhoea, epigastric pain. Rarely, blood disorders. Convulsions, sweating, myalgia, paraesthesias, extrapyramidal effects, tremor, sleep disturbances, depression, confusion, tinnitus, hypotension, hair loss.
Potentially Fatal: Anaphylaxis.

Drug Interactions

Enhanced sedation with alcohol or other CNS depressants. Additive antimuscarinic effects with MAOIs, atropine, TCAs. May mask warning symptoms caused by ototoxic agents e.g. aminoglycoside antibiotics.

Contraindications

Premature infants and neonates. Acute asthmatic attack.

Mode of actions

Mebhydrolin is an ethylenediamine derivative antihistamine with antimuscarinic and sedative properties.

Dosage & Administration

Adults and children over 10 years: 2-6 tablets daily
Children 5-10 years: 2-4 tablets daily
Children 2-5 years: 1-3 tablets daily
Children upto 2 years: 1-2 tablets daily

Pregnancy & Lactation

FDA has not yet classified the drug into a specified pregnancy category.