Precautions and warnings

Renal dysfunction, low phosphate diet, prolonged use.

Drug Interactions

Aluminium Hydroxide: Absorption is improved when combined with citrates or ascorbic acid. Allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine, phenytoin, phenothia.

Tetracyclines and biphosphonates are less absorbed when magnesium hydroxide is present. After about 2 hours, these and other medications should be administered separately.

Simethicon: None well documented.

Contraindications

Hypophosphataemia. Simethicone is used for renal failure, extremely debilitated individuals, and pregnant women in the first trimester.

Mode of actions

Aluminum hydroxide (AlCl3 salt + water) neutralizes stomach hydrochloride and raises gastric pH.

Magnesium hydroxide promotes bowel evacuation by producing osmotic fluid retention, causing the colon to distend with increased peristaltic activity; when combined with hydrochloric acid, it creates magnesium chloride.

Simethicone reduces the surface tension of gas bubbles, dispersing and preventing gas pockets in the GI system.

Dosage & Administration

Chew1-2 tablets or 2-4 tsf after meals and at bedtime as needed (up to 4 times a day) or as directed by a doctor.

Pregnancy & Lactation

FDA has not yet classified this medicine into a specified pregnancy category. Although there is no enough evidence that taking this medicine during you are pregnant is harmful.

Discuss with your doctor if you are trying to get pregnant while taking this medicine too.

If you do become pregnant while you are taking this medicine, you should continue to take it and contact with your doctors as quickly as possible. They can assist you to decide whether or not to keep taking this medicine. If you abandon taking this medicine and become sick, this would be more pernicious to your child than staying on the medication.


There is no specific information about whether this medicine is passed on to the baby through breast milk. During this medication, if your baby becomes very sleepy, restless, fatigued, exhibit feeding problems, stop breastfeeding and talk to your doctors very quickly.

Pack Size & Price