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Instina 40mg/5ml (Powder for Suspension)

Manufactured by: Ziska Pharmaceuticals Ltd.

Cefpodoxime Similar medicine

Instina is indicated for

  • Pharyngitis
  • Acute otitis media
  • Community-acquired pneumonia
  • Sinusitis
  • UTI
  • Cystitis
  • Gonorrhea
  • Skin
  • skin structure infections
  • Tonsillitis
  • Respiratory tract infections
  • Acute Maxillary Sinusitis
  • Acute bacterial exacerbation of chronic bronchitis

Precautions and warnings

Tell your doctor about any medical conditions you have, especially kidney disease, stomach or intestinal disease such as colitis, before using this drug.

Live bacterial vaccinations, such as the typhoid vaccine, may be affected by this medicine. Unless your doctor advises otherwise, do not get any vaccines or vaccinations while taking this drug.

Kidney function deteriorates as you age. The kidneys eliminate this medicine. As a result, elderly persons may be more susceptible to negative effects when using this medication.

Side-effects

  • Anaphylactic shock; purpuric nephritis
  • skin rash
  • pruritus; diarrhoea
  • nausea
  • abdominal pain
  • vomiting. Potentially Fatal: Pseudomembranous colitis; nephrotoxicity.

Drug Interactions

This medicine may cause erroneous test results in certain laboratory tests, such as the Coombs' test and certain urine glucose assays. Make sure your doctors are aware that you are taking this medication.

Cefpodoxime absorption may be hampered by antacids or H2-blockers. Renal excretion is inhibited by probenecid.

Renal function should be monitored during administration because it has the potential to be fatal. Furosemide has additive nephrotoxic effects.

Contraindications

Hypersensitivity to the active ingredient.

Mode of actions

Cefpodoxime binds to one or more penicillin-binding proteins (PBPs), which inhibits the last transpeptidation stage of peptidoglycan production in the bacterial cell wall, halting biosynthesis and causing bacterial cell death.

Dosage & Administration

Adult: PO Resp tract infections; UTI 100-200 mg 12 hrly. Skin infections 200-400 mg 12 hrly. Uncomplicated gonorrhoea 200 mg as a single dose.

Renal impairment: Patients on haemodialysis: Dose should be given after each dialysis session.
CrCl (ml/min) Dosage Recommendation
10-39 Increase dosing intervals to 24 hrly.

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.

Discuss with your doctors and tell them feedback about this medicine.

There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.

Pack Size & Price

50ml bot Price : ৳98

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Click here to see 124 more similar medicines

There are few similar medicines of Instina are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.