Livocard 75mg (Tablet)
Manufactured by: White Horse Pharma
Clopidogrel Similar medicine
Livocard is indicated for
- Coronary Artery Disease
- Acute coronary syndrome
- Myocardial infarction
- Peripheral vascular disease
- Cerebrovascular disease
- Atherosclerosis
- Thromboembolic disorders
- Unstable angina
- Stroke
Precautions and warnings
People with a higher risk of bleeding due to injury, surgery, ulcers, kidney or liver problems, or a history of bleeding or blood-clotting disorders should be cautious. This also applies to pregnant women.
Side-effects
- Dyspepsia
- abdominal pain
- nausea
- vomiting
- flatulence
- constipation
- gastritis
- gastric
- duodenal ulcers. GI upset
- diarrhoea
- paraesthesia
- vertigo
- headache
- dizziness
- pruritus
- rashes. Potentially Fatal: Bleeding disorders including GI
- intracranial haemorrhage. Blood dyscrasias.
Drug Interactions
Taking this medicine with NSAIDs can raise the risk of stomach and intestinal bleeding. Using a high dose of clopidogrel may also increase warfarin levels in the blood, which can cause more bleeding. High doses of clopidogrel can block the P450 (2C9) enzyme, which can affect how your body breaks down drugs like phenytoin, tamoxifen, torasemide, fluvastatin, and some NSAIDs. You should not use clopidogrel at the same time as drugs that block the CYP2C19 enzyme, such as omeprazole, esomeprazole, cimetidine, fluconazole, ketoconazole, voriconazole, etravirine, felbamate, fluoxetine, fluvoxamine, or ticlopidine.
Contraindications
Do not use if you are allergic (hypersensitive), have active abnormal bleeding, or have been given the medication within 7 days following a heart attack or ischemic stroke. Also avoid if you have bleeding or clotting (coagulation) disorders or are breastfeeding.
Mode of actions
Clopidogrel works by stopping adenosine diphosphate (ADP) from attaching to its receptors on platelets. This prevents the activation of the GP IIb/IIIa complex, which in turn blocks fibrinogen from binding and stops platelets from sticking together and forming clots.
Dosage & Administration
Adult: PO Prophylaxis of thromboembolic events 75 mg once daily.
Acute coronary syndrome For ST-elevation myocardial infarction: W/ aspirin: 75 mg once daily. Continue treatment for up to 28 days.
For unstable angina, non-ST-elevation myocardial infarction: Initial: 300 mg loading dose, followed by 75 mg once daily (w/ aspirin 75-325 mg once daily).
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.
Discuss with your doctors and tell them feedback about this medicine.
There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.
Pack Size & Price
30's pack Price : ৳270
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There are few similar medicines of Livocard are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
