Docexan 20mg/0.5ml (Injection)
Manufactured by: Beacon Pharmaceuticals Ltd.
Docetaxel Similar medicine
Docexan is indicated for
- Breast cancer
- Lung cancer
- Prostate cancer
- Stomach cancer
- Head/neck cancer
Precautions and warnings
Breastfeeding and liver problems: If you have liver issues, your doctor will regularly check your liver function and blood counts. It is also recommended to take 16 mg of oral dexamethasone each day for 3 days, starting one day before your docetaxel treatment.
Side-effects
- Erythematous patches
- eruptions
- scleroderma
- onycholysis
- alopoecia
- nausea
- vomiting
- diarrhoea
- stomatitis; increases in hepatic transaminases
- bilirubin
- alkaline phosphatase; mucositis
- asthenia
- arthralgia
- myalgia
- paroxysmal atrial tachycardia
- atrial flutter
- dysrrhythmia
- hypertension
- heart failure. Potentially Fatal: Neutropenia; fluid retention syndrome; anaemia.
Drug Interactions
Medicines that affect CYP3A4—whether they increase, decrease, or are broken down by this enzyme—can change how docetaxel is processed in the body.
Contraindications
Do not use if you have had a serious allergic reaction to docetaxel, its solvent, or polysorbate 80. Avoid use if you have severe neutropenia (very low white blood cell count), are pregnant, or have serious liver problems.
Mode of actions
Docetaxel works by interfering with the microtubules in cells, which are important for cell division and other cellular activities. It attaches to free tubulin, encourages these proteins to form stable microtubules, and prevents them from breaking down. As a result, this stops the cells from dividing.
Dosage & Administration
Adult: IV Breast cancer Initial: 60-100 mg/m2 once 3 wkly as a single agent.
Gastric adenocarcinoma; Head and neck cancer; Non-small cell lung cancer; Prostate cancer 75 mg/m2 once 3 wkly.
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
0.5 ml vial with solvent Price : ৳4000
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There are few similar medicines of Docexan are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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