H-Pen 250mg (Tablet)
Manufactured by: Hudson Pharmaceuticals Ltd.
Phenoxymethyl Penicillin Similar medicine
H-Pen is indicated for
- Tonsillitis
- Pharyngitis
- Skin & soft tissue infections
- Anthrax
- Lyme disease
- Rheumatic fever
- Spleen disorders
- Dental Abscesses
- gingivitis
- upper respiratory tract
- scarlet fever
- erysipelas
- otitis media
- Vincent's infection
Precautions and warnings
Phenoxymethyl Penicillin is an antibiotic medication. Before taking this medication, it is essential to take the following precautions:
Inform your healthcare provider if you are allergic to penicillin or any other antibiotics. If you have had an allergic reaction to penicillin in the past, your doctor may recommend an alternative medication.
Tell your doctor about any other medications you are taking, including prescription, over-the-counter, and herbal products. Some medications can interact with phenoxymethyl penicillin and cause unwanted side effects.
Inform your doctor if you have any medical conditions, such as kidney disease or liver disease, as phenoxymethyl penicillin can affect these conditions.
It is important to take phenoxymethyl penicillin exactly as prescribed by your doctor. Do not stop taking the medication before completing the full course of treatment, even if you start feeling better.
Phenoxymethyl penicillin may cause side effects such as diarrhea, nausea, or vomiting. If you experience any severe or persistent side effects, contact your doctor immediately.
If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before taking phenoxymethyl penicillin. The medication may harm the developing fetus or pass into breast milk and affect the nursing baby.
It is important to follow good hygiene practices, such as washing your hands regularly and covering your mouth and nose when coughing or sneezing, to prevent the spread of infection.
Side-effects
- Nausea
- vomiting
- epigastric distress
- diarrhoea
- black hairy tongue
- skin eruptions (maculopapular to exfoliative dermatitis)
- urticaria
- other serum-sickness like reactions
- laryngeal oedema
- fever
- eosinophilia
- Potentially Fatal: Anaphylaxis.
Drug Interactions
Phenoxymethyl penicillin can interact with other medications and potentially cause unwanted side effects or reduce the effectiveness of the medication. Some medications that may interact with phenoxymethyl penicillin include:
Probenecid: used to treat gout. It can increase the blood levels of phenoxymethyl penicillin, leading to an increased risk of side effects.
Methotrexate: used to treat cancer and autoimmune diseases. Phenoxymethyl penicillin can decrease the elimination of methotrexate from the body, leading to an increased risk of toxicity.
Oral contraceptives: phenoxymethyl penicillin can reduce the effectiveness of oral contraceptives, leading to an increased risk of unintended pregnancy.
Other antibiotics: concurrent use of other antibiotics may increase the risk of side effects or decrease the effectiveness of phenoxymethyl penicillin.
Contraindications
You should not take it if you have hypersensitivity to penicillins.
Mode of actions
Phenoxymethyl penicillin belongs to the group of antibiotics known as penicillins. It works by inhibiting the growth and replication of bacteria by disrupting bacterial cell wall synthesis. The active ingredient, phenoxymethyl penicillin, binds to and inhibits the enzyme transpeptidase, which is involved in the final stages of bacterial cell wall synthesis. This leads to the weakening of the bacterial cell wall, causing the bacteria to burst and die.
Phenoxymethyl penicillin is effective against a broad range of gram-positive bacteria, including Streptococcus, Staphylococcus, and some strains of Enterococcus. However, it is not effective against gram-negative bacteria, which have an outer membrane that protects them from the antibiotic.
Phenoxymethyl penicillin is absorbed well in the gastrointestinal tract and reaches peak levels in the blood within 1 to 2 hours after oral administration. The medication is eliminated primarily by the kidneys and has a half-life of approximately one hour.
It is important to note that phenoxymethyl penicillin can cause allergic reactions in some individuals. In such cases, the immune system overreacts to the antibiotic, leading to symptoms such as skin rash, itching, swelling, and difficulty breathing. If you experience any signs of an allergic reaction, seek medical attention immediately.
Dosage & Administration
Adult: 250-500 mg 6 hourly
Children: 125-250 mg 6 hourly
Dry Syrup: 1-2 tea-spoonful (5-10ml) 6 hourly
Forte Syrup: ½-1 tea-spoonful (2.5-5ml0 6 hourly
Infants: 62.5-125 mg 6 hourly
Adult: PO Prophylaxis of recurrent rheumatic fever 250 mg twice daily. Streptococcal infections of the upper respiratory tract, including scarlet fever and erysipelas 125-250 mg 6-8 hrly for 10 days.
Pneumococcal infections of the respiratory tract, including otitis media 250-500 mg 6 hrly until patient is afebrile for at least 2 days.
Fusospirochetosis (Vincent's infection) of the oropharynx; Staphylococcal infections of the skin and soft tissue 250-500 mg 6-8 hrly.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.
Discuss with your doctors and tell them feedback about this medicine.
There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.
Pack Size & Price
100's pack Price : ৳135
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