Manisol 20% IV (Infusion)
Manufactured by: Orion Pharma Ltd.
Mannitol 20% Similar medicine
Manisol 20% IV is indicated for
- Chronic bronchitis
- Cerebral oedema
- Oliguric phase of renal failure
- Raised intracranial pressure
- Renal function testing
- Transurethral prostatic resection
Precautions and warnings
Excess fluid in the body (hypervolaemia) or a blocked urinary tract may be concerns. Watch for signs of fluid and electrolyte imbalances. Do not use together with whole blood. Use with caution during pregnancy and breastfeeding.
Side-effects
- Fluid
- electrolyte imbalance; acidosis (with high doses). Nausea
- vomiting
- thirst; headache
- dizziness
- convulsions
- chills
- fever; tachycardia
- chest pain; blurred vision; urticaria
- hypotension or hypertension; acute renal failure; skin necrosis; thrombophloebitis.
Drug Interactions
Imbalances in fluids and electrolytes, and acidosis may happen with high doses. Other possible effects include nausea, vomiting, thirst, headache, dizziness, seizures, chills, fever, fast heartbeat, chest pain, blurred vision, rash, low or high blood pressure, sudden kidney failure, skin damage, and blood clots in the veins.
Contraindications
Fluid in the lungs (pulmonary congestion or edema); bleeding inside the skull (intracranial bleeding); heart failure (CHF); swelling caused by metabolism problems and weak blood vessels; no urine production due to serious kidney disease (anuria); and severe dehydration.
Mode of actions
Mannitol works by stopping the kidneys from reabsorbing water and electrolytes, which leads to increased urine production. It also raises the osmotic pressure in the blood, pulling water out of body tissues and into the bloodstream.
Dosage & Administration
Intravenous
Oliguric phase of renal failure
Adult: 50-100 g in a 24-hr period by IV infusion of a 5-25% solution. Adjust rate of administration to maintain a urine flow of at least 30-50 mL/hr.
Child: 0.25-2 g/kg.
Cerebral oedema
Adult: 0.25-2 g/kg by IV infusion of a 15-25% solution given over 30-60 minutes.
Reduction of raised intraocular pressure
Adult: 0.25-2 g/kg by IV infusion of a 15-25% solution given over 30-60 minutes.
Renal function testing
Adult: 0.2 g/kg infused over 3-5 min.
Irrigation
Transurethral prostatic resection
Adult: Use 2.5-5% solution for bladder irrigation.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
500ml bot Price : ৳125
Similar medicine
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