Omezole 20mg (Capsule)
Manufactured by: Medimet Pharmaceuticals Ltd.
Omeprazole Similar medicine
Omezole is indicated for
- Peptic ulcer
- H. pylori infection
- Gastro-oesophageal reflux disease
- Zollinger-Ellison syndrome
- Oesophagitis
- Acid-related dyspepsia
- NSAID-associated ulceration
Precautions and warnings
This medicine is not suitable for patients with malignancy, hepatic impairment. pregnancy, a mother who feeds breast milk to her baby and children.
Tell your doctor or pharmacist about your medical history, especially if you have liver disease or lupus, before using this drug.
Some symptoms could be warning indications of a more serious ailment. If you have heartburn with lightheadedness, sweating, or dizziness, pain, especially with shortness of breath, unusual perspiration, or unexplained weight loss, seek medical attention right away.
If you have any of these signs of a serious condition, such as pain swallowing food, bloody vomit, vomit that looks like coffee grounds, black stools, heartburn for more than four months, frequent chest pain, frequent wheezing (especially with heartburn), nausea and vomiting, or stomach pain, seek medical help right away.
Proton pump inhibitors may increase your chance of bone fractures, especially if you use them for a long time, at larger doses, or if you're older. Discuss strategies to prevent bone loss with your doctors, such as taking calcium and vitamin D supplements.
The drug's adverse effects, particularly bone loss and fractures, may be more severe in older persons.
Side-effects
- Diarrhoea
- nausea
- fatigue
- constipation
- vomiting
- flatulence
- acid regurgitation
- taste perversion
- arthralgia
- myalgia
- urticaria
- dry mouth
- dizziness
- headache
- paraesthesia
- abdominal pain
- skin rashes
- weakness
- back pain
- upper respiratory infection
- cough. Potentially Fatal: Anaphylaxis.
Drug Interactions
Cilostazol, clopidogrel, methotrexate, and rifampin are some of the drugs that may interact with this one.
Some products require stomach acid to be adequately absorbed by the body. Because omeprazole lowers stomach acid, it may affect how effectively these medications perform. Atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirine, and certain azole antifungals like itraconazole, ketoconazole, and posaconazole are among the products affected.
Esomeprazole and omeprazole are quite similar. While taking omeprazole, avoid taking any drugs that include esomeprazole.
Potentially fatal: Rilpivirine, nelfinavir, and atazanavir plasma concentrations and pharmacological effects may be reduced.
Contraindications
Known hypersensitivity to any of its components.
Mode of actions
Omeprazole, popularly known as PPI, is a substituted benzimidazole stomach antisecretory drug. It inhibits the final step in gastric acid production by inhibiting the H+/K+ ATPase enzyme system on the gastric parietal cell's secretory surface. Acid is blocked at both the basal and stimulated levels.
Dosage & Administration
Adult: PO Peptic ulcer 20 mg once daily. Severe: 40 mg/day. Duration: Duodenal ulcers: 4 wk; Gastric ulcers: 8 wk. Maintenance: 10-20 mg once daily. NSAID-associated ulceration 20 mg/day.
Eradication of H. pylori infection Dose varies w/ regimen: 20 mg once daily or 40 mg/day in 1-2 divided doses. To use w/ antibiotics. GERD 20 mg once daily for 4 wk, may continue for another 8 wk if needed. Maintenance: 10 mg/day. Zollinger-Ellison syndrome Initial: 60 mg once daily. Maintenance: 20-120 mg/day. Give doses >80 mg in 2 divided doses.
Prophylaxis of acid aspiration during general anesth Initial: 40 mg the evening before surgery and another 40 mg 2-6 hr pre-op. Acid-related dyspepsia 10 or 20 mg/day 2-4 wkly. Erosive oesophagitis 20 mg/day for 4-8 wk. Maintenance: 20 mg/day for up to 12 mth of total therapy inclusive of treatment period.
IV Gastric and duodenal ulcers; Reflux oesophagitis 40 mg once daily. Prophylaxis of acid aspiration during general anesth 40 mg, to be completed 1 hr before the surgery.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
50's pack/56's pack/100's pack Price : ৳200/224/400
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Click here to see 207 more similar medicines
There are few similar medicines of Omezole are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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