Precautions and warnings

Congestive heart disease: Using clopidogrel at the same time has not been tested for safety or effectiveness. Use during pregnancy and breastfeeding is not established.

Drug Interactions

Taking cilostazol together with other medicines that affect the enzymes CYP3A4 (such as erythromycin, other macrolide antibiotics, and diltiazem) or CYP2C19 (such as omeprazole) can change how cilostazol is processed in the body.

Contraindications

Heart failure; a tendency to bleed; a history of abnormal heart rhythms; a long QT interval; serious kidney problems; moderate to severe liver problems.

Mode of actions

Cilostazol is a medicine that blocks an enzyme called phosphodiesterase-III (PDE-III) in a selective and reversible way. By doing this, it stops the breakdown of a substance in the body called cyclic adenosine monophosphate (cAMP). Higher levels of cAMP in blood platelets and blood vessels prevent platelets from clumping together and help blood vessels relax and widen. Additionally, cilostazol stops cells from taking up adenosine, which further boosts cAMP levels due to its effect on PDE-III.

Dosage & Administration

Adult: PO 100 mg twice daily.

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.

Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.

This medicine passes into breast milk. Talk to your doctor before breastfeeding.

Pack Size & Price