Bet-CL (Ointment)
Manufactured by: Acme Laboratories Ltd.
Betamethasone 0.1% + Clotrimazole 1% Topical Similar medicine
Bet-CL is indicated for
- 腳癬、腿癬、癬、腳癬、股癬。
Precautions and warnings
外用皮質類固醇可引起下視丘-腦下垂體-腎上腺 (HPA) 軸的可逆性抑制，如果停止治療，可能會導致糖皮質激素不足。 有些患者在治療期間局部皮質類固醇的全身性吸收可能導致庫欣氏症候群、高血糖和醣尿。
大面積使用、連續使用以及在封閉敷料下使用都是增加全身吸收的條件。
如果偵測到 HPA 軸抑制，則應停藥、減少用藥頻率或改用效力較低的皮質類固醇。
由於皮膚表面積與體重之比較大，兒科患者可能對等劑量的全身毒性較敏感。
Side-effects
- 臨床試驗中報告的克黴唑二丙酸倍他米松乳膏的不良反應為 1.9% 的患者出現感覺異常，以及皮疹、水腫和繼發性感染，各不到 1% 的患者。 據報道，外用皮質類固醇會出現以下局部不良反應，並且在使用封閉敷料時可能會更頻繁地發生。 在兒科族群中，報告的克黴唑和二丙酸倍他米松乳膏的不良事件包括生長遲緩、良性顱內高壓、庫欣氏症候群（HPA 軸抑制）和局部皮膚反應，包括皮膚萎縮。 局部皮質類固醇的全身性吸收導致可逆性下視丘-腦下垂體-腎上腺（HPA）軸抑制，在一些患者中出現庫欣氏症候群、高血糖和糖尿的表現。 使用克黴唑的不良反應如下：紅斑、刺痛、起泡、脫皮、水腫、搔癢、蕁麻疹和一般皮膚刺激。
Contraindications
對克黴唑、二丙酸倍他米松、其他皮質類固醇、咪唑或這些產品中的任何其他物質過敏的患者。
Mode of actions
倍他米松是一種皮質類固醇，主要起糖皮質激素的作用。 它降低蛋白質合成速率，抑制多形核白血球和纖維母細胞的遷移，並逆轉毛細血管通透性和溶酶體穩定性，以預防和調節發炎。
克黴唑是一種真菌抗真菌藥物，可與真菌細胞膜中的磷脂質結合。 透過改變細胞壁的滲透性，它會導致關鍵的細胞內成分的損失。
Dosage & Administration
將足夠的克黴唑和二丙酸倍他米松乳膏輕輕按摩到受影響的皮膚區域，每天早晚兩次。
Pregnancy & Lactation
懷孕期間不允許使用這種藥物。 如果您懷孕了，請勿使用它。 它可以透過皮膚和肺部吸收，從而損害未出生孩子的器官並導致先天性殘疾。 治療期間及停藥後六個月內嚴格有效的節育。 如果您確實懷孕了，請停止服用此藥並立即與您的醫生討論。
沒有關於這種藥物是否會進入母乳的具體資訊。 考慮到兒童可能存在的風險，不建議在使用該藥物時進行母乳喂養，並且至少在最後一次用藥後兩週進行母乳喂養。 哺乳前請先諮詢您的醫生。
Pack Size & Price
10gm tube Price : ৳29
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