Neoral 25mg (Capsule)
Manufactured by: Novartis (Bangladesh) Ltd.
Ciclosporin Similar medicine
Neoral is indicated for
- Organ transplantation
- Atopic dermatitis
- Psoriasis
- Rheumatoid arthritis
- Nephrotic syndrome
- Bone marrow transplantation
- Urticaria
- Ulcerative colitis
Precautions and warnings
If you have kidney or liver problems, high uric acid levels, a history of allergies or severe allergic reactions, or if you are pregnant, use this medicine with caution. Your blood pressure, blood electrolytes, kidney, and liver function should be regularly checked.
Side-effects
- Hypertension; hepatoxicity; tremor; paraesthesia
- hypertrichosis
- facial oedema
- acne; gingival hypertrophy; hyperkalaemia
- fluid retention; increased susceptibility to infections; GI symptoms. Potentially Fatal: Nephrotoxicity; convulsions.
Drug Interactions
Some medicines can increase the levels of ciclosporin in your body, including diltiazem, doxycycline, erythromycin, ketoconazole, high doses of methylprednisolone, nicardipine, verapamil, and oral contraceptives. Other medicines can lower ciclosporin levels, such as carbamazepine, isoniazid, phenobarbitone, phenytoin, and rifampicin. There is a higher risk of having convulsions (seizures) if you take ciclosporin with high doses of methylprednisolone.
**Warning:** Taking ciclosporin with certain drugs like aminoglycosides, amphotericin B, ciprofloxacin, colchicine, melphalan, co-trimoxazole, or NSAIDs can increase the risk of serious kidney damage.
Contraindications
Hypersensitivity; malignant neoplasms; uncontrolled hypertension; psoriasis; lactation.
Mode of actions
Cyclosporine is a powerful medicine that weakens the immune system, mainly by affecting helper T-cells. It works by blocking calcineurin and lowering the amount of interleukin-2 produced, which reduces the body’s immune response.
Dosage & Administration
Adult: PO Immunosuppression in organ transplant Initial: 10-15 mg/kg/day, starting 4-12 hr pre-op and continue for 1-2 wk. Maintenance: 2-6 mg/kg/day. Psoriasis; Severe atopic dermatitis 2.5 mg/kg/day. Max: 5 mg/kg/day. Rheumatoid arthritis 2.5 mg/kg/day for 6-8 wk. Max: 4 mg/kg/day. Nephrotic syndrome 5 mg/kg/day. IV Prevention of graft rejection in bone marrow transplantation Initial: 3-5 mg/kg/day starting on the day before transplant, continue for up to 2 wk until maintenance via oral administration. Organ transplantation Initial: 5-6 mg/kg/day as a single dose infusion. Transfer to oral administration as soon as possible.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
50's pack Price : ৳2950
Similar medicine
Manufactured by: Novartis (Bangladesh) Ltd.
Manufactured by: Novartis (Bangladesh) Ltd.
Manufactured by: Novartis (Bangladesh) Ltd.
Manufactured by: Novartis (Bangladesh) Ltd.
Manufactured by: Novartis (Bangladesh) Ltd.
Click here to see more similar medicines
There are few similar medicines of Neoral are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
