Precautions and warnings

Suicidal ideation and depression worsening. Mania, dementia, and lactose intolerance are all symptoms of lactose intolerance. It's possible that it'll affect your capacity to drive or operate machinery. Lactation and pregnancy. Adolescents and children

Contraindications

Potent CYP1A2 inhibitors in combination (eg fluvoxamine or ciprofloxacin). Hepatic dysfunction.

Mode of actions

Agomelatine is a melatonin receptor agonist (MT1 and MT2) as well as a 5-hydroxytryptamine receptor (5-HT2C) antagonist. Resynchronization of circadian rhythms, augmentation of dopaminergic and adrenergic input to the frontal cortex, induction of neurogenesis, and other processes all function in a complementary and possibly synergistic manner to ameliorate depressed states. Additionally, melatonergic agonism and 5-HT2C receptor antagonism work together to improve anxiety symptoms, sleep, and sexual function.

Dosage & Administration

25-50 mg at bedtime.

Pregnancy & Lactation

FDA has not yet classified this medicine into a specified pregnancy category. Although there is no enough evidence that taking this medicine during you are pregnant is harmful.

Discuss with your doctor if you are trying to get pregnant while taking this medicine too.

If you do become pregnant while you are taking this medicine, you should continue to take it and contact with your doctors as quickly as possible. They can assist you to decide whether or not to keep taking this medicine. If you abandon taking this medicine and become sick, this would be more pernicious to your child than staying on the medication.


There is no specific information about whether this medicine is passed on to the baby through breast milk. During this medication, if your baby becomes very sleepy, restless, fatigued, exhibit feeding problems, stop breastfeeding and talk to your doctors very quickly.

Pack Size & Price