Dofixim 40mg (Suspension)
Manufactured by: Ibn Sina Pharmaceutical Ind. Ltd.
Cefpodoxime Similar medicine
Dofixim is indicated for
- Pharyngitis
- akute Mittelohrentzündung
- ambulant erworbene Pneumonie
- Sinusitis
- Harnwegsinfektionen
- Zystitis
- Gonorrhoe
- Infektionen der Haut und der Hautstruktur
- Mandelentzündung
- Infektionen der Atemwege
- akute Sinusitis maxillaris
- akute bakterielle Verschlimmerung einer chronischen Bronchitis
Precautions and warnings
Informieren Sie Ihren Arzt vor der Anwendung dieses Arzneimittels über alle Erkrankungen, an denen Sie leiden, insbesondere über Nierenerkrankungen, Magen- oder Darmerkrankungen wie Kolitis.
Lebendimpfungen gegen Bakterien, wie z. B. die Typhusimpfung, können durch dieses Arzneimittel beeinträchtigt werden. Sofern Ihr Arzt Ihnen nichts anderes verordnet, sollten Sie sich während der Einnahme dieses Arzneimittels nicht impfen lassen oder sich impfen lassen.
Mit zunehmendem Alter lässt die Nierenfunktion nach. Die Nieren scheiden dieses Arzneimittel aus. Daher sind ältere Menschen möglicherweise anfälliger für negative Auswirkungen, wenn sie dieses Medikament einnehmen.
Side-effects
- Anaphylaktischer Schock; Purpurnephritis
- Hautausschlag
- Pruritus; Durchfall
- Übelkeit
- Bauchschmerzen
- Erbrechen. Potenziell tödlich: Pseudomembranöse Kolitis; Nephrotoxizität.
Drug Interactions
Dieses Arzneimittel kann bei bestimmten Labortests, wie dem Coombs-Test und bestimmten Uringlukosetests, zu fehlerhaften Testergebnissen führen. Stellen Sie sicher, dass Ihre Ärzte wissen, dass Sie dieses Medikament einnehmen.
Die Resorption von Cefpodoxim kann durch Antazida oder H2-Blocker beeinträchtigt werden. Die renale Ausscheidung wird durch Probenecid gehemmt.
Die Nierenfunktion sollte während der Verabreichung überwacht werden, da sie möglicherweise tödlich sein kann. Furosemid hat additive nephrotoxische Wirkungen.
Contraindications
Überempfindlichkeit gegen den Wirkstoff.
Mode of actions
Cefpodoxim bindet an ein oder mehrere Penicillin-bindende Proteine (PBPs), wodurch die letzte Transpeptidierungsstufe der Peptidoglycan-Produktion in der Bakterienzellwand gehemmt wird, wodurch die Biosynthese gestoppt und der Zelltod der Bakterien verursacht wird.
Dosage & Administration
Erwachsener: PO Infektionen des Resp-Trakts; Harnwegsinfektion 100-200 mg 12 Stunden. Hautinfektionen 200–400 mg 12 Stunden. Unkomplizierter Gonorrhoe 200 mg als Einzeldosis.
Nierenfunktionsstörung: Hämodialysepatienten: Die Dosis sollte nach jeder Dialysesitzung verabreicht werden.
CrCl (ml/min) Dosierungsempfehlung
10-39 Dosierungsintervalle auf 24 Stunden erhöhen.
Pregnancy & Lactation
Obwohl Reproduktionsstudien an Tieren eine schädliche Wirkung gezeigt haben, konnte das Risiko für den Fötus manchmal sogar nicht nachgewiesen werden, und es gibt keine ausreichenden und gut kontrollierten Studien bei schwangeren Frauen. Während der Schwangerschaft kann dieses Arzneimittel jedoch nur dann angewendet werden, wenn dies unbedingt erforderlich ist.
Besprechen Sie dies mit Ihren Ärzten und teilen Sie ihnen Feedback zu diesem Arzneimittel mit.
Es liegen keine spezifischen Informationen darüber vor, ob dieses Arzneimittel über die Muttermilch auf das Baby übertragen wird. Besprechen Sie dies mit Ihrem Arzt, bevor Sie stillen.
Pack Size & Price
50 ml bot Price : ৳100
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