Apegestrol 160mg (Tablet)
Manufactured by: Techno Drugs Ltd.
Megestrol Acetate Similar medicine
Apegestrol is indicated for
- Contraception
- Breast carcinoma
- Endometrial carcinoma
- Anorexia
- Cachexia
Precautions and warnings
A history of blood clots, mild to moderate liver problems, risk of fluid buildup, past depression, diabetes, high blood pressure, or kidney or heart issues.
Side-effects
- Acne
- urticaria
- fluid retention
- wt gain
- heart failure
- nausea
- vomiting
- GI disturbances
- changes in libido
- breast discomfort
- premenstrual symptoms
- irregular menstrual cycles
- depression
- insomnia
- somnolence
- alopoecia
- hirsutism
- anaphylactoid-like reaction
- jaundice
- hot flushes
- adrenocortical suppression
- nausea
- carpal tunnel syndrome
- hypercalcaemia
- tumour flare
- hypertension.
Drug Interactions
Indinavir levels in the body may go down. Cisplatin might not work as well. Warfarin could stay in the body longer. Aminoglutethimide and drugs that increase enzyme activity may lower megestrol levels.
Contraindications
Pregnancy and lactation. Severe hepatic impairment.
Mode of actions
Megestrol is a type of progestogen that is used to treat certain cancers and to help increase appetite. While it’s not clear exactly how megestrol works against cancer, it may do so by reducing the production of estrogen, affecting other hormones in the body, or possibly acting directly to kill cancer cells.
Dosage & Administration
Adult: PO Palliation of breast carcinoma 40 mg 4 times/day. Palliation of endometrial carcinoma 40-320 mg/day in divided doses. Anorexia and cachexia in patients w/ cancer or AIDS Initial: 800 mg/day. Usual: 400-800 mg/day.
Pregnancy & Lactation
This medicine must not be used during pregnancy. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict two effective types of birth control starting one month before and during treatment and for three years after stopping this medicine. Discuss with your doctors if you are not sure which types of birth control are effective for you. You must need to take pregnancy tests regularly during your treatment with this medicine and for at least three years after taking this medicine. If it seems that you do become pregnant stop taking this medicine and call your doctor immediately. If you really become pregnant, miss a menstrual period, or have sex without using two forms of birth control. In some cases, your doctor can prescribe emergency contraception to prevent pregnancy. People on this medicine should not donate blood during the treatment and for three years afterward.
This medicine is also contraindicated breast milk. Breastfeeding is not recommended while using this medication and for three years afterward.
Pack Size & Price
Price : ৳
Similar medicine
Manufactured by: Laboratorio Varifarma, Argentina
Manufactured by: Techno Drugs Ltd.
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There are few similar medicines of Apegestrol are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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