Precautions and warnings

Use caution in patients with sick sinus syndrome, heart conduction problems, or respiratory diseases. Cholinergic stimulation can increase stomach acid. This medicine may make urinary blockages and seizures worse. Use with care during pregnancy, in people with kidney problems, or those with mild to moderate liver problems—monitor body weight. Be careful with asthma or other lung diseases, since breathing problems may get worse. It may also make movement problems (extrapyramidal symptoms) worse. Use caution if breastfeeding.

Drug Interactions

Do not use this medication with other cholinomimetic drugs, as they can affect how anticholinergic medicines work. It may also increase the effects of succinylcholine-type muscle relaxants used during anesthesia. Smoking tobacco can cause your body to get rid of this medicine faster.

Contraindications

Allergy to other carbamate medicines. Serious liver problems.

Mode of actions

Rivastigmine works by temporarily blocking enzymes called cholinesterases that break down acetylcholine, a chemical important for brain function. This increases the amount of acetylcholine in the central nervous system (CNS). Rivastigmine mainly affects the brain and is used to help manage symptoms of dementia in people with Alzheimer's disease and Parkinson's disease.

Dosage & Administration

Oral
Mild to moderately severe dementia in Alzheimer's disease
Adult: Initially, 1.5 mg bid, increased according to response by 1.5 mg bid at intervals of at least 2 wk. If treatment is interrupted for >a few days, restart at 1.5 mg bid and increase dose accordingly, if required. Max: 6 mg bid.

Transdermal

Indicated for mild, moderate, and severe dementia of the Alzheimer's type
Initial: Apply 4.6 mg q24hr
Dose titration: May increase dose to 9.5 mg q24hr after a minimum 4 weeks if well tolerated; after an additional 4 weeks, may further increase to 13.3 mg patch if needed
Mild-to-moderate Alzheimer disease: Effective dosage range is 9.5-13.3 mg/24 hr
Moderate-to-severe Alzheimer disease: Effective dose is 13.3 mg/24 hr
Replace with new patch q24hr

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.

Discuss with your doctors and tell them feedback about this medicine.

There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.

Pack Size & Price