Precautions and warnings

Pregnancy. Liver or kidney problems; hemophilia A or B; diabetes. Watch for signs of abnormal fat distribution (lipodystrophy).

Drug Interactions

**Drug Interactions:**

- **These medicines can lower the effectiveness/levels:** antacids, phenobarbital, carbamazepine, aminoglutethimide, phenytoin, rifampicin, nafcillin, nevirapine, and omeprazole.
- **These medicines can increase the effectiveness/levels:** azole antifungal drugs, cimetidine, and efavirenz.
- **This drug can increase the effects or levels of:** azithromycin, calcium channel blockers, clarithromycin, corticosteroids (like fluticasone), mirtazapine, nateglinide, nefazodone, ciclosporin, sirolimus, tacrolimus, venlafaxine, eplerenone, fentanyl, atorvastatin, PDE-5 inhibitors, rifabutin, trazodone, tricyclic antidepressants (TCAs).
- **This drug can lower the effects or levels of:** hormonal contraceptives, methadone, and theophylline-like drugs.

**Serious (Potentially Fatal) Interactions:**
- Can dangerously increase the effects or side effects of: amiodarone, cisapride, pimozide, midazolam, triazolam, ergot alkaloids, lovastatin, simvastatin, and quinidine.

Mode of actions

Nelfinavir is a medicine that blocks a specific enzyme called HIV protease, which is needed by the HIV-1 virus to mature and spread. By stopping this enzyme from working, nelfinavir prevents the virus from making infectious copies of itself.

Dosage & Administration

Oral
HIV infection
Adult: Combined with other antiretrovirals: 1.25 g bid or 0.75 g tid.
Child: Combined with other antiretrovirals: 2-13 yr: 45-55 mg/kg bid or 25-35 mg/kg tid. Max: 0.75 g tid.
Max Dosage: Child: 0.75 g tid.
Hepatic impairment: Dose reduction may be required.

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.

Discuss with your doctors and tell them feedback about this medicine.

There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.

Pack Size & Price