Locopain (Eye Drops)
Manufactured by: Asiatic Laboratories Ltd.
Diclofenac Sodium 0.1% Eye prep Similar medicine
Locopain is indicated for
- Allergic conjunctivitis
- Ocular inflammation
- Miosis
Precautions and warnings
Diclofenac eye drops can hide the symptoms of an eye infection. Because of this, doctors need to watch carefully for any signs of infection in patients using these drops. If the drops are used for a long time, doctors should regularly check the eyes, including eye pressure. Also, people should not wear contact lenses while being treated with diclofenac eye drops.
Side-effects
- Mild to moderate burning sensation in 5-15% patients which is transient in nature
- almost never necessitated discontinuation of treatment. Other less common side-effects are sensitivity to light
- bad taste
- feeling of pressure
- allergic reactions etc.
Drug Interactions
Diclofenac can raise the amount of methotrexate in the blood. Taking it with other NSAIDs or blood thinners (like warfarin) can increase the risk of stomach bleeding. There is a higher chance of kidney problems if used with ciclosporin or triamterene. If a person already has serious corneal (eye) inflammation, using diclofenac eye drops together with corticosteroid eye drops can raise the risk of corneal problems. Colestyramine and colestipol make diclofenac less effective by lowering the amount your body absorbs. Sucralfate can also lower diclofenac levels if taken together. Diclofenac eye drops may make acetylcholine and carbachol eye drops work less well. Finally, diclofenac may increase the levels of lithium and digoxin in the blood.
Contraindications
This medicine should not be used by anyone who is allergic to Diclofenac Sodium or any of its ingredients. It is also not safe for people who have experienced asthma, hives, or a stuffy/runny nose after taking NSAIDs (non-steroidal anti-inflammatory drugs).
Mode of actions
It blocks the enzymes COX-1 and COX-2, which stops the body from making prostaglandins. It may also prevent white blood cells called neutrophils from clumping together and becoming active, reduce the movement of immune cells to sites of inflammation, lower levels of substances that cause inflammation, and change how certain immune cells called lymphocytes work.
Dosage & Administration
Adults
Pre-operatively: Instill 1 drop in the conjunctival sac up to 5 times over the 3 hours preceding surgery
Post-operatively: Instill 1 drop in the conjunctival sac after 15, 30 & 45 minutes following surgery; then 3-5 times daily for as long as required.
Inflammatory conditions: Instill 1 drop in the conjunctival sac 4-5 times daily depending upon the severity of the diseases.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
5 ml drop Price : ৳80
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