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Gemifloy 320mg (Tablet)

Manufactured by: Popular Pharmaceuticals Ltd.

Gemefloxacin Similar medicine

Gemifloy is indicated for

  • Chronic bronchitis
  • Community-acquired pneumonia

Precautions and warnings

If someone has a history of a prolonged QT interval, untreated problems with their body’s electrolytes, or nervous system conditions like epilepsy, they should be careful. It’s important to stay well-hydrated. There is a higher chance of developing a rash if the treatment lasts a long time. These concerns are especially important for children.

Side-effects

  • Diarrhoea
  • nausea
  • vomiting; headache
  • dizziness; rash
  • urticaria. May cause elevation of liver enzymes.

Drug Interactions

There is a higher risk of QT interval prolongation when this drug is taken with class IA (such as quinidine) or class III (such as amiodarone) antiarrhythmic drugs, and with other medications that can also lengthen the QT interval (like erythromycin, tricyclic antidepressants, and antipsychotics). Probenecid can reduce this drug's removal from the body by the kidneys. Absorption of this medicine can decrease if it is taken with antacids containing aluminum or magnesium, buffered didanosine, sucralfate, or dietary supplements with metals like zinc, magnesium, or iron. Older adults over 60, especially those also using corticosteroids, have a higher risk of serious tendon problems. This medication may also increase the effects of warfarin, potentially raising prothrombin time, INR, and the risk of bleeding.

Contraindications

Allergy: Do not use in patients who are allergic or hypersensitive to this medicine, or in those who are currently taking class IA or class III antiarrhythmic drugs.

Mode of actions

Gemifloxacin kills bacteria by blocking two important enzymes, topoisomerase II (also called DNA gyrase) and topoisomerase IV. These enzymes are needed for bacteria to copy, repair, and use their DNA. Without them, the bacteria cannot survive.

Dosage & Administration

Adult: PO Acute bacterial exacerbation of chronic bronchitis 320 mg once daily for 5 days.
Community-acquired pneumonia 320 mg once daily for 7 days.

Renal impairment:
CrCl (ml/min)

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.

Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.

This medicine passes into breast milk. Talk to your doctor before breastfeeding.

Pack Size & Price

10's pack Price : ৳552.5

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There are few similar medicines of Gemifloy are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.