Loreta 2.5mg (Tablet)
Manufactured by: Popular Pharmaceuticals Ltd.
Letrozole Similar medicine
Loreta is indicated for
- Breast cancer
Precautions and warnings
Serious kidney problems, serious liver problems, and osteoporosis—use with caution. Be careful when driving or using machines.
Side-effects
- Hot flushes
- arthralgia
- nausea
- vomiting
- fatigue
- dizziness
- headache
- dyspepsia
- constipation
- diarrhoea
- anorexia
- alopoecia
- increased sweating
- rash
- peripheral oedema
- osteoporosis
- musculoskeletal pain
- vaginal irritation. Potentially Fatal: Thromboembolic events.
Drug Interactions
Plasma levels reduced by tamoxifen.
Contraindications
Premenopausal women and children; hypersensitivity.
Mode of actions
Letrozole attaches itself to the heme part of the aromatase enzyme, which normally changes androgens into estrogen. By blocking this enzyme, letrozole lowers the amount of estrogen in the blood.
Dosage & Administration
Adult: PO Adjuvant therapy for post menopausal women with hormone receptor positive early breast cancer; Advanced breast cancer in postmenopausal women 2.5 mg once daily.
Hepatic impairment: Reduce dose by 50% in patients with cirrhosis and severe hepatic impairment; recommended dose: 2.5 mg on alternate days.
Pregnancy & Lactation
This medicine must not be used during pregnancy. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict two effective types of birth control starting one month before and during treatment and for three years after stopping this medicine. Discuss with your doctors if you are not sure which types of birth control are effective for you. You must need to take pregnancy tests regularly during your treatment with this medicine and for at least three years after taking this medicine. If it seems that you do become pregnant stop taking this medicine and call your doctor immediately. If you really become pregnant, miss a menstrual period, or have sex without using two forms of birth control. In some cases, your doctor can prescribe emergency contraception to prevent pregnancy. People on this medicine should not donate blood during the treatment and for three years afterward.
This medicine is also contraindicated breast milk. Breastfeeding is not recommended while using this medication and for three years afterward.
Pack Size & Price
10's pack Price : ৳400
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Click here to see 2 more similar medicines
There are few similar medicines of Loreta are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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