Olmetic 20mg (Tablet)
Manufactured by: Drug International Ltd.
Olmesartan Medoxomil Similar medicine
Olmetic is indicated for
- Hipertensi
- Nefropati diabetik
Precautions and warnings
Obat-obatan yang mempengaruhi sistem renin-angiotensin dapat membahayakan atau bahkan membunuh janin jika dikonsumsi pada trimester ke-2 dan ke-3 kehamilan. Hentikan penggunaan olmesartan medoxomil segera setelah Anda mengetahui bahwa Anda hamil. Beberapa orang, terutama yang kekurangan cairan tubuh atau garam, mungkin mengalami tekanan darah rendah. Jarang terjadi, obat ini dapat menyebabkan produksi urin rendah, penumpukan limbah dalam darah, dan gagal ginjal mendadak. Orang dengan arteri yang menyempit di ginjalnya mempunyai risiko lebih besar untuk mengalami tekanan darah rendah yang parah dan masalah ginjal. Jika Anda memiliki masalah ginjal, gunakan obat ini dengan hati-hati dan periksa kadar kreatinin dan kalium darah Anda secara teratur. Jangan gunakan jika Anda memiliki masalah ginjal parah (CrCl< 20 mL/menit) atau masalah hati. Hati-hati jika Anda mempunyai masalah katup jantung atau otot jantung yang menebal. Obat ini mungkin tidak bekerja dengan baik untuk orang dengan kondisi yang disebut aldosteronisme primer. Hal ini juga tidak dianjurkan saat menyusui.
Side-effects
- Pusing
- sakit kepala
- sakit perut
- pencernaan yg terganggu
- diare
- gastroenteritis
- mual
- nyeri dada
- bronkitis
- batuk
- faringitis
- rinitis
- radang sendi
- sakit punggung
- kelelahan
- gejala mirip flu
- hipotensi
- edema perifer
- hematuria
- ISK
- hiperkalemia
- hipertrigliseridemia
- hiperurisemia
- peningkatan enzim hati
- edema wajah
- angioedema
- dan rhabdomyolysis. Berpotensi Fatal: Gagal ginjal akut.
Drug Interactions
Ada kemungkinan lebih tinggi terjadinya kadar kalium tinggi (hiperkalemia) jika obat ini dikonsumsi dengan penghambat ACE, diuretik hemat kalium, suplemen kalium, atau obat lain yang meningkatkan kalium (seperti siklosporin atau eplerenon). Mengonsumsinya dengan obat tekanan darah lain dapat membuat tekanan darah Anda semakin turun. Menggunakannya dengan NSAID dapat menurunkan fungsi ginjal dan dapat menyebabkan gagal ginjal mendadak. Ini juga dapat meningkatkan kadar litium dalam darah Anda, sehingga meningkatkan risiko toksisitas litium.
Contraindications
Kehamilan (trimester ke-2 dan ke-3); obstruksi bilier.
Mode of actions
Olmesartan adalah obat yang bekerja dengan cara memblokir reseptor spesifik (AT1) untuk hormon yang disebut angiotensin II. Hormon ini biasanya menyebabkan pembuluh darah mengencang dan membuat tubuh melepaskan hormon lain yang disebut aldosteron. Dengan menghalangi efek ini, olmesartan membantu merelaksasi dan memperlebar pembuluh darah, sehingga menurunkan tekanan darah dan memungkinkan lebih banyak darah dan oksigen mencapai jantung.
Dosage & Administration
Lisan
Hipertensi
Dewasa: Awal: 10-20 mg sekali sehari kemudian dapat ditingkatkan hingga maksimal 40 mg sekali sehari jika diperlukan.
Anak: 6-16 tahun 35 kg: 20 mg sekali sehari. Dosis dapat digandakan satu kali jika perlu setelah 2 minggu.
Lansia: Tidak diperlukan penyesuaian dosis.
Gangguan hati: Sedang: Awal: 10 mg sekali sehari dapat ditingkatkan hingga maksimal 20 mg sekali sehari.
Pregnancy & Lactation
Obat ini tidak diperbolehkan selama kehamilan. Jangan gunakan jika Anda sedang hamil. Dapat diserap melalui kulit dan paru-paru sehingga dapat merusak organ tubuh anak Anda yang belum lahir dan menyebabkan cacat bawaan. Alat kontrasepsi yang efektif dan ketat selama pengobatan dan selama enam bulan setelah menghentikan obat ini. Jika Anda hamil, hentikan penggunaan obat ini dan segera diskusikan dengan dokter Anda.
Belum ada informasi spesifik apakah obat ini masuk ke dalam ASI atau tidak. Mengingat kemungkinan risiko pada anak-anak, menyusui saat menggunakan obat ini tidak dianjurkan dan setidaknya dua minggu setelah dosis terakhir. Konsultasikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
30's pack Price : ৳240
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