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Zocil 100mg (Tablet)

Manufactured by: Beximco Pharmaceuticals Ltd.

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Zocil is indicated for

  • 週邊血管疾病、間歇性跛行

Precautions and warnings

充血性心臟病:同時使用氯吡格雷尚未經過安全性或有效性測試。 懷孕和哺乳期間的使用尚未確定。

Side-effects

  • 頭痛、頭暈、心悸、腹瀉、大便異常;疼痛、感染;週邊水腫、噁心、嘔吐、其他心律不整、胸痛、鼻炎、咽炎、瘀斑和皮疹。

Drug Interactions

將西洛他唑與其他影響酵素 CYP3A4(例如紅黴素、其他大環內酯類抗生素和地爾硫卓)或 CYP2C19(例如奧美拉唑)的藥物一起服用可以改變西洛他唑在體內的加工方式。

Contraindications

心臟衰竭;有出血傾向;有心律異常病史;QT間期長;嚴重的腎臟問題;中度至重度肝臟問題。

Mode of actions

西洛他唑是一種以選擇性和可逆方式阻斷磷酸二酯酶-III (PDE-III) 酶的藥物。 透過這樣做,它可以阻止體內一種稱為環磷酸腺苷 (cAMP) 的物質的分解。 血小板和血管中較高水平的 cAMP 可以防止血小板聚集在一起,並幫助血管放鬆和擴張。 此外,西洛他唑可阻止細胞攝取腺苷,從而因其對 PDE-III 的影響而進一步提高 cAMP 水平。

Dosage & Administration

成人:PO 100 mg,每日兩次。

Pregnancy & Lactation

雖然動物生殖研究顯示對胎兒有不良影響,並且在孕婦中沒有充分且良好對照的研究,但在懷孕期間,儘管存在潛在風險,但在確實需要時可以使用該藥物。

在懷孕最後 3 個月內使用這種藥物的新生兒母親可能很少會出現困倦、肌肉僵硬或顫抖、餵食或呼吸困難、持續哭泣等症狀。 如果您發現寶寶有任何這些症狀,尤其是在第一個月內,請立即告訴醫生。

這種藥物會進入母乳。 哺乳前請先諮詢您的醫生。

Pack Size & Price

20's pack Price : ৳240

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There are few similar medicines of Zocil are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.