Terbex 250mg (Tablet)
Manufactured by: Beximco Pharmaceuticals Ltd.
Terbinafine Similar medicine
Terbex is indicated for
- Teigne du pied
- Teigne de la jambe
- Teigne du corps
- Dermatophytose
- Infections des ongles
Precautions and warnings
Si vous souffrez déjà de problèmes hépatiques ou rénaux, ou si vous êtes enceinte, des soins particuliers sont nécessaires. Assurez-vous de faire tester votre fonction hépatique avant de commencer un traitement oral.
Side-effects
- Anorexie
- nausées
- douleurs abdominales
- troubles du goût
- diarrhée
- éruption cutanée
- urticaire. Potentiellement mortel : insuffisance hépatique
- syndrome de Stevens-Johnson
- neutropénie.
Drug Interactions
Les médicaments dégradés par l'enzyme CYP450 2D6 peuvent avoir des taux plus élevés lorsqu'ils sont pris avec de la terbinafine. La rifampicine peut réduire la quantité de terbinafine dans l'organisme, tandis que la cimétidine peut augmenter les niveaux de terbinafine.
Contraindications
Hypersensibilité, maladie hépatique active ou chronique, lactation.
Mode of actions
La terbinafine agit en bloquant la squalène époxydase, une enzyme importante dont les champignons ont besoin pour fabriquer des stérols pour leurs parois cellulaires. Cela empêche le champignon de produire de l'ergostérol, un élément clé de sa paroi cellulaire, entraînant la mort des cellules fongiques. La terbinafine est efficace pour tuer les dermatophytes (un type de champignon qui provoque des infections cutanées) et certains types de levures.
Dosage & Administration
Orale
Dermatophytose
Adulte : 250 mg une fois par jour pendant 2 à 4 semaines pour la teigne cruris, 6 semaines pour la teigne pédicelle, 4 semaines pour la teigne corporis et 6 à 12 semaines pour les infections des ongles.
Enfant : 10-20 kg : 62,5 mg ; 20-40 kg : 125 mg ; > 40 kg : 250 mg. Doses à prendre une fois par jour. Le traitement est généralement administré pendant 2 semaines pour la teigne de la tête ; 2 à 4 semaines pour la teigne cruris ; 4 semaines pour la teigne corporelle ; 6 semaines en teigne des pieds ; 6 à 12 semaines pour les infections des ongles.
Insuffisance rénale :
ClCr (ml/min)
Pregnancy & Lactation
Bien que les études sur la reproduction animale aient montré un effet indésirable, même parfois sans pouvoir démontrer le risque pour le fœtus et qu'il n'existe pas d'études adéquates et bien contrôlées chez la femme enceinte, ce médicament peut être utilisé pendant la grossesse juste en cas de nécessité absolue.
Discutez avec vos médecins et faites-leur part de vos commentaires sur ce médicament.
Il n'existe aucune information spécifique indiquant si ce médicament est transmis au bébé par le lait maternel. Discutez-en avec votre médecin avant d'allaiter.
Pack Size & Price
10's pack Price : ৳500
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