Veracal 40 40mg (Tablet)
Manufactured by: Incepta Pharmaceuticals Ltd.
Verapamil Hydrochloride Similar medicine
Veracal 40 is indicated for
- Essential hypertension
- Angina pectoris
- prevention of re-infarction
- Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias
- Atrial fibrillation with rapid ventricular response (except WPWS)
- Atrial flutter with rapid conduction
- Extrasystoles
- Acute hypertension
- Acute coronary insufficiency
- For the prophylaxis
- / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia
- in the application of adrenaline in halothane anaesthesia respectively.
Precautions and warnings
Be cautious when dealing with first-degree AV block or slow heart rates (bradycardia).
Side-effects
- Verapamil is generally well tolerated. The following reaction to orally administered Verapamil appeared clearly drug related or occurred at rates greater than 1% in clinical trials with approximately 5000 patients.Digestive system: Constipation
- nausea;Cardiovascular system: Hypotension
- edema
- CHF
- pulmonary edema
- bradycardia
- AV block;Respiratory system: Upper respiratory tract infections;Nervous system: Dizziness
- headache
- fatigue;Skin: Rash
- flashing;Hepatic: Elevated liver enzyme.
Drug Interactions
**Drug Interactions with Verapamil:**
- **Beta-blockers and flecainide:** Can increase the heart-slowing effects.
- **Digoxin:** Higher chance of slow heartbeat, heart rhythm problems, and digoxin toxicity.
- **Remifentanil and sufentanil:** Greater risk of a slow heartbeat and low blood pressure.
- **Everolimus:** Levels of both drugs may increase when used together.
- **Other drugs (doxorubicin, buspirone, carbamazepine, ciclosporin, epirubicin, eplerenone, quinidine, statins, sirolimus, tacrolimus, quinupristin/dalfopristin):** Their levels may go up if taken with verapamil.
- **Alcohol:** Verapamil can increase blood alcohol levels.
- **Lithium:** Effects are unpredictable.
- **Phenobarbital, sulfinpyrazone, rifampicin, rifabutin, rifapentine:** Can lower verapamil levels.
- **Protease inhibitors, cimetidine:** Can raise verapamil levels.
**Serious or Life-Threatening Interactions:**
- **Amiodarone:** May greatly increase heart-slowing effects.
- **Dofetilide, ranolazine, sertindole:** Higher risk of dangerous heart rhythm (QT prolongation).
- **Ivabradine:** Can cause even slower heartbeat.
- **Clonidine:** Greater risk of serious heart block.
- **Dantrolene:** Risk of life-threatening high potassium and heart failure.
Contraindications
Verapamil should not be used in the following cases:
- Severe problems with left heart pumping, very low blood pressure, or cardiogenic shock
- Sick sinus syndrome (unless the patient has a working artificial pacemaker)
- Second or third-degree heart block (unless there is a working artificial pacemaker)
- Patients with atrial flutter or atrial fibrillation who also have an extra electrical pathway in the heart (such as Wolff-Parkinson-White or Lown-Ganong-Levine syndrome)
- Patients who are allergic to verapamil hydrochloride
Verapamil injection should not be given through a vein (IV) to patients who are taking beta-blockers (unless in an intensive care unit) or those who have a known allergy to verapamil hydrochloride.
Mode of actions
Verapamil works by blocking calcium from entering the muscle cells of the arteries, heart muscle, and heart’s electrical system. This helps stop and prevent spasms in the coronary arteries, lowers blood pressure by widening blood vessels, and reduces the workload on the heart. In patients with chronic atrial flutter or fibrillation, verapamil slows the heart rate, and it also helps prevent sudden episodes of fast heart rhythms (paroxysmal supraventricular tachycardia). Overall, verapamil lowers blood pressure, eases chest pain (angina), and slows the electrical signals passing through the heart’s AV node.
Dosage & Administration
Oral: The dose of Verapamil should be individualized by titration and the drug should be administered with food.
For essential hypertension the initial dose should be given 180 mg in the morning. If adequate response is not obtained with 180 mg of Verapamil then the dose may be titrated by following manner:
240 mg each morning.
180 mg each morning plus 180 mg each evening.
240 mg every 12 hourly.
For angina the usual dose is 80 mg to 120 mg three times a day.
For arrythmias in digitalized patients, Verapamil should be given 240 mg to 360 mg in divided doses, depending on the severity of the condition. Divided doses up to 180 mg/day may occasionally be needed.
Intravenous: Adults: 5mg slowly intravenously, in tachycardias and hypertensive crises, if necessary repeat after 5 to 10 minutes.
Drip infusion to maintain the therapeutic effect: 5-10 mg/hour in physiological saline, glucose, laevulose or similar solutions, on average up to a total dose of 100mg/day.
Children: Newborn 0.75-1mg (= 0.3-0.4ml)
Infants 0.75-2mg (= 0.3-0.8ml)
Children age 1-5 years: 2-3mg (= 0.8-1.2ml)
age 6-14 years: 2.5-5mg (= 1-2ml) of Verapamil, given intravenously, depending on age and action.
The injection should be made slowly under electrocardiographic control and only until onset of the effect.
Intravenous infusion in hypertensive crises: initially 0.05-0.1mg/kg/hour; if the effect proves to be insufficient, the dose is increased at 30-60 minute intervals until twice the dose or more is reached. Average total dose up to 1.5mg/kg/day.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
50's pack Price : ৳112.5
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Manufactured by: Incepta Pharmaceuticals Ltd.
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Manufactured by: Incepta Pharmaceuticals Ltd.
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There are few similar medicines of Veracal 40 are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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Verapamil Hydrochloride is indicated for Essential hypertension, Angina pectoris and prevention of re-infarction, Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias, Atrial fibrillation with rapid ventricular response (except WPWS) , Atrial flutter with rapid conduction, Extrasystoles, Acute hypertension, Acute coronary insufficiency, For the prophylaxis and / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia and in the application of adrenaline in halothane anaesthesia respectively.
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Are you looking medicine for Angina pectoris and prevention of re-infarction ?
Verapamil Hydrochloride is indicated for Essential hypertension, Angina pectoris and prevention of re-infarction, Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias, Atrial fibrillation with rapid ventricular response (except WPWS) , Atrial flutter with rapid conduction, Extrasystoles, Acute hypertension, Acute coronary insufficiency, For the prophylaxis and / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia and in the application of adrenaline in halothane anaesthesia respectively.
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Are you looking medicine for Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias ?
Verapamil Hydrochloride is indicated for Essential hypertension, Angina pectoris and prevention of re-infarction, Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias, Atrial fibrillation with rapid ventricular response (except WPWS) , Atrial flutter with rapid conduction, Extrasystoles, Acute hypertension, Acute coronary insufficiency, For the prophylaxis and / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia and in the application of adrenaline in halothane anaesthesia respectively.
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Verapamil Hydrochloride is indicated for Essential hypertension, Angina pectoris and prevention of re-infarction, Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias, Atrial fibrillation with rapid ventricular response (except WPWS) , Atrial flutter with rapid conduction, Extrasystoles, Acute hypertension, Acute coronary insufficiency, For the prophylaxis and / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia and in the application of adrenaline in halothane anaesthesia respectively.
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Verapamil Hydrochloride is indicated for Essential hypertension, Angina pectoris and prevention of re-infarction, Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias, Atrial fibrillation with rapid ventricular response (except WPWS) , Atrial flutter with rapid conduction, Extrasystoles, Acute hypertension, Acute coronary insufficiency, For the prophylaxis and / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia and in the application of adrenaline in halothane anaesthesia respectively.
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Verapamil Hydrochloride is indicated for Essential hypertension, Angina pectoris and prevention of re-infarction, Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias, Atrial fibrillation with rapid ventricular response (except WPWS) , Atrial flutter with rapid conduction, Extrasystoles, Acute hypertension, Acute coronary insufficiency, For the prophylaxis and / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia and in the application of adrenaline in halothane anaesthesia respectively.
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Are you looking medicine for Acute hypertension ?
Verapamil Hydrochloride is indicated for Essential hypertension, Angina pectoris and prevention of re-infarction, Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias, Atrial fibrillation with rapid ventricular response (except WPWS) , Atrial flutter with rapid conduction, Extrasystoles, Acute hypertension, Acute coronary insufficiency, For the prophylaxis and / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia and in the application of adrenaline in halothane anaesthesia respectively.
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Verapamil Hydrochloride is indicated for Essential hypertension, Angina pectoris and prevention of re-infarction, Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias, Atrial fibrillation with rapid ventricular response (except WPWS) , Atrial flutter with rapid conduction, Extrasystoles, Acute hypertension, Acute coronary insufficiency, For the prophylaxis and / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia and in the application of adrenaline in halothane anaesthesia respectively.
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Verapamil Hydrochloride is indicated for Essential hypertension, Angina pectoris and prevention of re-infarction, Supraventricular arrhythmias. Paroxysmal supraventricular tachycardias, Atrial fibrillation with rapid ventricular response (except WPWS) , Atrial flutter with rapid conduction, Extrasystoles, Acute hypertension, Acute coronary insufficiency, For the prophylaxis and / or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia and in the application of adrenaline in halothane anaesthesia respectively.
List of medicines using Verapamil Hydrochloride
