Atrogen 1 gm/100 ml (Eye Drops)
Manufactured by: General Pharmaceuticals Ltd.
Atropine Sulphate Similar medicine
Atrogen is indicated for
- Bradycardia
- Organophosphorus poisoning
- Anesthesia adjunct
Precautions and warnings
Reflux oesophagitis is a condition that affects the elderly, Pregnancy, newborns, and children.
Side-effects
- Dry mouth
- dysphagia
- constipation
- flushing
- dryness of skin
- tachycardia
- palpitations
- arrhythmias
- mydriasis
- photophobia
- cycloplegia
- raised intraocular pressure. Toxic doses cause tachycardia
- hyperpyrexia
- restlessness
- confusion
- excitement
- hallucinations
- delirium
- may progress to circulatory failure
- resp depression. Eye drops: Systemic toxicity esp in children
- on prolonged use may lead to irritation
- hyperaemia
- oedema
- conjunctivitis. Increased intraocular pressure. Inhalation: Dryness of mouth
- throat. Potentially Fatal: Atrial arrhythmias
- AV dissociation
- multiple ventricular ectopics.
Drug Interactions
Quinidine, antidepressants, and several antihistamines have additive anticholinergic effects.
Contraindications
Glaucoma, chronic obstructive pulmonary disease, sick sinus syndrome, thyrotoxicosis, heart failure, pyloric stenosis, and prostatic hypertrophy are some of the conditions that can affect men.
Mode of actions
Atropine is an anticholinergic drug that inhibits muscarinic receptors in peripheral tissues such as the heart, intestines, bronchial muscles, iris, and secretory glands. There may be some central stimulation. Atropine relieves heart block caused by vagal activity and eliminates bradycardia. The smooth muscles of the bronchi and gut relax, and glandular secretions decrease. It also has a cycloplegic and mydriatic impact.
Dosage & Administration
Adult: IV Bradycardia 500 mcg every 3-5 mins. Total: 3 mg.
IV/IM Organophosphorus poisoning 2 mg every 10-30 mins until muscarinic effects disappear or atropine toxicity appears.
Child: 20 mcg/kg given every 5-10 minutes.
IM/SC Premed in anesth 300-600 mcg 30-60 mins before anesth.
Child: >20 kg: 300-600 mcg; 12-16 kg: 300 mcg; 7-9 kg: 200 mcg; >3 kg: 100 mcg. Doses to be given via IM/SC admin 30-60 minutes before anaesthesia.
IV/IM/SC Poisoning or overdosage w/ compd having muscarinic actions 0.6-1 mg, repeat 2 hrly.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
Price : ৳
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There are few similar medicines of Atrogen are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
