Seroquet-25 25mg (Tablet)
Manufactured by: Unimed & Unihealth Manufacturers Ltd.
Quetiapine Similar medicine
Seroquet-25 is indicated for
- Schizophrenia
- Bipolar disorder
Precautions and warnings
People with cerebrovascular disease or who are prone to low blood pressure should use caution. Extra care is needed for those with a history of seizures, neuroleptic malignant syndrome, or tardive dyskinesia. Blood sugar levels need to be watched closely, especially in people with diabetes. If you have liver or kidney problems, use this medicine carefully. It’s best to stop taking it slowly rather than all at once. Watch out for signs of feeling worse, having suicidal thoughts, or any unusual changes in behaviour. This medication should also be used with caution during pregnancy or while breastfeeding.
Side-effects
- Headache
- asthenia
- abdominal pain
- back pain
- fever
- chest pain
- postural
- orthostatic hypotension
- hypertension
- constipation
- dry mouth
- dyspepsia
- diarrhoea
- leucopenia
- elevations in serum transaminase level
- weight gain
- myalgia
- somnolence
- dizziness
- anxiety
- rhinitis
- rash
- dry skin
- ear pain
- UTI
- syncope
- neuroleptic malignant syndrome
- variations in WBC count
- neutropenia
- eosinophilia
- elevations in nonfasting serum triglyceride level
- total cholesterol
- decrease in thyroid hormone levels
- prolongation of the QTc interval.
Drug Interactions
Using quetiapine with alcohol can make you feel more drowsy and cause low blood pressure when standing up. Certain medications, like phenytoin and carbamazepine (which boost CYP3A4 activity), can lower the amount of quetiapine in your blood. Others, like ketoconazole and erythromycin (which block CYP3A4), can raise its levels in your blood.
Contraindications
Quetiapine should not be used by people who are allergic to it or any of its ingredients. It is also not safe for anyone with severe central nervous system (CNS) depression, bone marrow suppression, or who is in a coma.
Mode of actions
Quetiapine works by blocking several types of receptors in the brain, including serotonin (5-HT1A and 5-HT2), dopamine (D1 and D2), histamine (H1), and adrenergic (alpha-1 and alpha-2) receptors. It is commonly used to treat conditions like schizophrenia and bipolar disorder.
Dosage & Administration
Adult: PO Schizophrenia Initial: 25 mg twice daily on day 1, increase to 50 mg twice daily on day 2, 100 mg twice daily on day 3 and 150 mg twice daily on day 4. Usual: 300-450 mg/day. Max: 750 mg/day.
Bipolar disorder: Manic phase: 50 mg twice daily, increase by 50 mg/dose for each subsequent day till 3rd day. Usual: 400-800 mg/day. Increase slowly if needed.
Depressive phase: Initial: 50 mg at bedtime on day 1, 100 mg on day 2, 200 mg on day 3, and 300 mg on day 4. May increase to 400 mg on day 5 and 600 mg on day 8 if needed.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
30's pack Price : ৳90
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Click here to see 7 more similar medicines
There are few similar medicines of Seroquet-25 are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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