Telfin 250mg (Tablet)
Manufactured by: UniDerma
Terbinafine Similar medicine
Telfin is indicated for
- Ringelflechte am Fuß
- Ringelflechte am Bein
- Ringelflechte am Körper
- Dermatophytose
- Nagelinfektionen
Precautions and warnings
Wenn bei Ihnen Leber- oder Nierenprobleme bestehen oder Sie schwanger sind, ist besondere Vorsicht geboten. Lassen Sie unbedingt Ihre Leberfunktion testen, bevor Sie mit der oralen Behandlung beginnen.
Side-effects
- Anorexie
- Übelkeit
- Bauchschmerzen
- Geschmacksstörungen
- Durchfall
- Hautausschlag
- Urtikaria. Potenziell tödlich: Leberversagen
- Stevens-Johnson-Syndrom
- Neutropenie.
Drug Interactions
Arzneimittel, die durch das Enzym CYP450 2D6 abgebaut werden, können bei Einnahme mit Terbinafin höhere Werte aufweisen. Rifampicin kann die Menge an Terbinafin im Körper senken, während Cimetidin den Terbinafinspiegel erhöhen kann.
Contraindications
Überempfindlichkeit, aktive oder chronische Lebererkrankung, Stillzeit.
Mode of actions
Terbinafin blockiert die Squalenepoxidase, ein wichtiges Enzym, das Pilze zur Herstellung von Sterinen für ihre Zellwände benötigen. Dadurch wird verhindert, dass der Pilz Ergosterol, einen Schlüsselbestandteil seiner Zellwand, produziert, was zum Absterben der Pilzzellen führt. Terbinafin ist wirksam bei der Abtötung von Dermatophyten (einer Pilzart, die Hautinfektionen verursacht) und einigen Hefearten.
Dosage & Administration
Mündlich
Dermatophytose
Erwachsene: 250 mg einmal täglich für 2–4 Wochen bei Tinea cruris, 6 Wochen bei Tinea pedis, 4 Wochen bei Tinea corporis und 6–12 Wochen bei Nagelinfektionen.
Kind: 10–20 kg: 62,5 mg; 20-40 kg: 125 mg; >40 kg: 250 mg. Einmal täglich einzunehmende Dosen. Die Behandlung der Tinea capitis dauert in der Regel zwei Wochen. 2–4 Wochen bei Tinea cruris; 4 Wochen bei Tinea corporis; 6 Wochen bei Tinea pedis; 6–12 Wochen bei Nagelinfektionen.
Nierenfunktionsstörung:
CrCl (ml/min)
Pregnancy & Lactation
Obwohl tierexperimentelle Reproduktionsstudien eine nachteilige Wirkung gezeigt haben und manchmal sogar kein Risiko für den Fötus nachgewiesen werden konnte, und es keine ausreichenden und gut kontrollierten Studien bei schwangeren Frauen gibt, kann dieses Arzneimittel während der Schwangerschaft nur dann angewendet werden, wenn dies unbedingt erforderlich ist.
Besprechen Sie dies mit Ihren Ärzten und teilen Sie ihnen Feedback zu diesem Arzneimittel mit.
Es liegen keine spezifischen Informationen darüber vor, ob dieses Arzneimittel über die Muttermilch auf das Baby übertragen wird. Besprechen Sie dies mit Ihrem Arzt, bevor Sie stillen.
Pack Size & Price
10's pack Price : ৳300
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