Tobasol 300 mg/5 ml (Solution)
Manufactured by: Beximco Pharmaceuticals Ltd.
Tobramycin Sulphate Similar medicine
Tobasol is indicated for
- Cystic fibrosis
Precautions and warnings
People with existing kidney, hearing, or balance problems; those who are dehydrated; individuals with muscle weakness or disorders like myasthenia gravis or Parkinson’s disease; newborn babies; older adults; and women who are breastfeeding should use caution.
Side-effects
- Nausea
- vomiting
- dizziness or vertigo
- acute renal failure
- interstitial nephritis
- acute tubular necrosis
- electrolyte imbalances
- purpura
- encephalopathy
- convulsions
- mental depression
- hallucinations
- ototoxicity
- blood dyscrasias
- increased LFT
- bilirubin concentrations.
Drug Interactions
Using etacrynic acid, furosemide, other aminoglycosides, cefalotin, cisplatin, vancomycin, piperacillin, ciclosporin, or amphotericin B together can increase the risk of kidney or ear damage. Miconazole may lower the amount of tobramycin in the blood.
Warning: Using magnesium or other medicines that block nerve-muscle signals at the same time can dangerously increase neuromuscular-blocking effects.
Mode of actions
Tobramycin works by attaching to the 30S part of bacterial ribosomes, which stops the bacteria from making proteins they need to survive. It is effective against many types of bacteria that need oxygen to grow, especially gram-negative ones, and some gram-positive bacteria. However, it does not work against Chlamydia, fungi, viruses, or most bacteria that grow without oxygen (anaerobic bacteria).
Dosage & Administration
Inhalation
Cystic fibrosis
Adult: 300 mg every 12 hr inhaled from a suitable nebuliser for 28 days, then stop for 28 days and repeat in cycles of 28 days as needed. Do not give doses
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
50's pack Price : ৳500
Similar medicine
Manufactured by: Beximco Pharmaceuticals Ltd.
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There are few similar medicines of Tobasol are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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