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ACE XR 665mg (Tablet)

Manufactured by: Square Pharmaceuticals Ltd.

Paracetamol Similar medicine

ACE XR is indicated for

  • Mild to moderate pain
  • fever

Precautions and warnings

Renal or hepatic impairment, particularly in the case of liver disease, and alcohol addiction.

Sugar or aspartame may be present in liquid formulations, chewable pills, or dissolving/effervescent tablets and powders. If you have diabetes, phenylketonuria, or any other condition that requires you to limit or avoid these compounds in your diet, you should proceed with caution. Ask your doctor or pharmacist about using these items safely if you have any of these conditions.

Side-effects

  • Nausea
  • allergic reactions
  • skin rashes
  • acute renal tubular necrosis. Potentially Fatal: Very rare
  • blood dyscrasias (e.g. thrombocytopenia
  • leucopenia
  • neutropenia
  • agranulocytosis); liver damage.

Drug Interactions

Paracetamol is a commonly used analgesic and antipyretic medicine that is readily available both via prescription and over-the-counter (OTC). Fortunately, there have been few clinically significant medication interactions identified. Hepatotoxicity from an overdose of the paracetamol metabolite NAPQI is likely to be exacerbated by enzyme-inducing medications. Because of inconsistencies between observational studies and those in healthy volunteers, there is a lot of debate about the potential for warfarin to interact with it and boost its anticoagulant effects. Aside from that, no severe medication interactions with therapeutic doses of paracetamol have been documented in humans.

Because of its low risk of causing allergic reactions, this drug can be administered in patients who are intolerant to salicylates and those with allergic tendencies, including bronchial asthmatics. When giving paracetamol to children, specific dose instructions must be followed.

Contraindications

Hypersensitivity to the active ingredient.

Mode of actions

Paracetamol acts as an analgesic by inhibiting the production of pain impulses in the peripheral nervous system. Antipyresis is caused by the inhibition of the hypothalamus heat-regulating region. Its ineffective anti-inflammatory properties are due to the suppression of prostaglandin production in the central nervous system.

Dosage & Administration

Tablet
Adult: 1 - 2 tablets every 4 to 6 hours up to a maximum of 4 g (8 tablets) daily
Children (6 - 12 years) : 1/2 to 1 tablet 3 to 4 times daily

Syrup
Children: 2 months: 60 mg (1/2 measuring spoonful) for post immunization pyrexia;
Under 3 months (on doctor's advice only) : 10 mg/kg (5 mg/kg if jaundiced)
3 months - 1 year : 60 - 120 mg (1/2 - 1 measuring spoonful),
1 - 5 years : 1 - 2 measuring spoonful
6 - 12 years : 2 - 4 measuring spoonful

Paediatric Drops
Children Up to 3 months: 0.5 ml (40 mg)
4 to 11 months: 1.0 ml (80 mg)
1 to 2 years: 1.5 ml (120 mg)
2 to 3 years: 2 ml (160mg)
4 to 5 years: 3 ml (240 mg)
Dose can be repeated, every 4 hours.

For Suppository: Suppository should be administered rectally.
Children: 3 months-1 year: 60-125 mg
1-5 years: 125-250 mg
5-12 years: 250-500 mg
These doses may be repeated every 4-6 hours as necessary (maximum 4 doses in 24 hours).
Adults & children over 12 years: 500 mg-1 g every 4-6 hours to a maximum of 4 g daily.

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.

Discuss with your doctors and tell them feedback about this medicine.

There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.

Pack Size & Price

100's pack Price : ৳150

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There are some similar medicines of ACE XR are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.

Are you looking medicine for Mild to moderate pain and fever ?

Paracetamol

Indicated for Mild to moderate pain and fever

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1 more generic are used for Mild to moderate pain and fever

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