Xpa XR is indicated for
Mild to moderate pain
Precautions and warnings
Renal or hepatic impairment, particularly in the case of liver disease, and alcohol addiction.
Sugar or aspartame may be present in liquid formulations, chewable pills, or dissolving/effervescent tablets and powders. If you have diabetes, phenylketonuria, or any other condition that requires you to limit or avoid these compounds in your diet, you should proceed with caution. Ask your doctor or pharmacist about using these items safely if you have any of these conditions.
- allergic reactions
- skin rashes
- acute renal tubular necrosis.
Potentially Fatal: Very rare
- blood dyscrasias (e.g. thrombocytopenia
- agranulocytosis); liver damage.
Paracetamol is a commonly used analgesic and antipyretic medicine that is readily available both via prescription and over-the-counter (OTC). Fortunately, there have been few clinically significant medication interactions identified. Hepatotoxicity from an overdose of the paracetamol metabolite NAPQI is likely to be exacerbated by enzyme-inducing medications. Because of inconsistencies between observational studies and those in healthy volunteers, there is a lot of debate about the potential for warfarin to interact with it and boost its anticoagulant effects. Aside from that, no severe medication interactions with therapeutic doses of paracetamol have been documented in humans.
Because of its low risk of causing allergic reactions, this drug can be administered in patients who are intolerant to salicylates and those with allergic tendencies, including bronchial asthmatics. When giving paracetamol to children, specific dose instructions must be followed.
Hypersensitivity to the active ingredient.
Mode of actions
Paracetamol acts as an analgesic by inhibiting the production of pain impulses in the peripheral nervous system. Antipyresis is caused by the inhibition of the hypothalamus heat-regulating region. Its ineffective anti-inflammatory properties are due to the suppression of prostaglandin production in the central nervous system.
Dosage & Administration
Adult: 1 - 2 tablets every 4 to 6 hours up to a maximum of 4 g (8 tablets) daily
Children (6 - 12 years) : 1/2 to 1 tablet 3 to 4 times daily
Children: 2 months: 60 mg (1/2 measuring spoonful) for post immunization pyrexia;
Under 3 months (on doctor's advice only) : 10 mg/kg (5 mg/kg if jaundiced)
3 months - 1 year : 60 - 120 mg (1/2 - 1 measuring spoonful),
1 - 5 years : 1 - 2 measuring spoonful
6 - 12 years : 2 - 4 measuring spoonful
Children Up to 3 months: 0.5 ml (40 mg)
4 to 11 months: 1.0 ml (80 mg)
1 to 2 years: 1.5 ml (120 mg)
2 to 3 years: 2 ml (160mg)
4 to 5 years: 3 ml (240 mg)
Dose can be repeated, every 4 hours.
For Suppository: Suppository should be administered rectally.
Children: 3 months-1 year: 60-125 mg
1-5 years: 125-250 mg
5-12 years: 250-500 mg
These doses may be repeated every 4-6 hours as necessary (maximum 4 doses in 24 hours).
Adults & children over 12 years: 500 mg-1 g every 4-6 hours to a maximum of 4 g daily.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.
Discuss with your doctors and tell them feedback about this medicine.
There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.
Pack Size & Price
The information available on this medicine is only for informational purposes.
Never take Xpa XR without consulting the doctor.
Even, don’t take Xpa XR which has been given by the doctor for other persons
although you guys have the same disease. The above price of Xpa XR may differ
from the actual price in the local market for a variety of reasons, including local taxes and other factors.
This is the only approximate indicative price of this medicine.