Acifix 20mg (Tablet)
Manufactured by: Beximco Pharmaceuticals Ltd.
Rabeprazole Similar medicine
Acifix is indicated for
- 消化性潰瘍、幽門螺旋桿菌感染、胃食道逆流、小兒胃食道逆流症
Precautions and warnings
請勿拆開、咀嚼或壓碎雷貝拉唑鈉片。
Side-effects
- 一般來說，雷貝拉唑在短期和長期研究中均具有良好的耐受性。 雷貝拉唑有時可能會引起頭痛、腹瀉、腹痛、嘔吐、便秘、口乾、食慾增加或減少、肌肉疼痛、嗜睡、頭暈。
Drug Interactions
這種藥物可能會降低血液中酮康唑、伊曲康唑和氯吡格雷的含量。 與利尿劑或地高辛一起服用會增加鎂水平低的風險。 它也可能使華法林發揮更強的作用，增加凝血酶原時間和 INR。 它可以提高血液中沙奎那韋和甲氨蝶呤的水平，但硫糖鋁可以降低其自身水平。
嚴重警告：它可能會降低利匹韋林和阿扎那韋的用量和作用，這可能是危險的。
Contraindications
對雷貝拉唑、其他質子幫浦抑制劑 (PPI) 或藥物中任何成分過敏的人不應使用雷貝拉唑。
Mode of actions
雷貝拉唑是一種稱為質子幫浦抑制劑（PPI）的藥物。 它透過阻斷一種稱為 H+/K+ ATP 酶的酶來減少胃產生的酸量，這種酶存在於某些胃細胞的表面。
Dosage & Administration
i) 十二指腸潰瘍：早上服用 20 毫克片劑，治療 4 週，可治癒十二指腸潰瘍並緩解症狀。 大多數患者在 4 週內痊癒。
ii) 良性胃潰瘍：每天早上 20 mg，持續 6 週，如果未完全治愈，則再持續 6 週。
iii) 與幽門螺旋桿菌感染相關的十二指腸潰瘍和良性胃潰瘍：雷貝拉唑與阿莫西林和克拉黴素聯合作為三藥方案，用於治療幽門螺旋桿菌感染和十二指腸潰瘍病患者。 雷貝拉唑比其他質子幫浦抑制劑提供更快的治療選擇，每天一次 20 毫克，可持續長達 10 至 14 天。
iv) 治癒糜爛性或潰瘍性胃食道逆流症 (GERD)：每天早上 20 毫克，持續 4 至 8 週。 治療8週後仍未痊癒的患者，可考慮額外服用8週的雷貝拉唑療程。
v) 有症狀 GERD 的治療：建議成人口服劑量為 20 mg，每日一次，持續 4 週。 如果 4 週後症狀未完全緩解，可考慮額外的療程。
vi) 維持糜爛性或潰瘍性 GERD 的癒合：適用於維持糜爛性或潰瘍性 GERD 的患者維持癒合並減少胃灼熱症狀的復發率。 對照研究持續時間不超過 12 個月。
vii) 預防或治療 NSAID 引起的潰瘍：接受 NSAID 治療的患者每日一次 20 mg 片劑。
viii) 佐林格-埃利森症候群：建議成人口服起始劑量為 60 mg，每天一次。 應根據患者個別需求調整劑量，並應依臨床指示持續服用。 有些患者可能需要分次服用。 已給予的劑量高達 100 mg 每日一次和 60 mg 每日兩次。
ix) 兒科 GERD：1 至 11 歲兒科患者 GERD 的治療：以體重計算 1 至 11 歲兒科患者的建議劑量為：
• 體重低於15 公斤：每天一次5 毫克，持續長達12 週，若反應不足，可選擇增加至10 毫克。
• 15 公斤或以上：10 毫克，每天一次，持續長達12 週。
Pregnancy & Lactation
雖然動物生殖研究顯示出不良影響，甚至有時無法證明對胎兒的風險，並且在孕婦中沒有充分和良好對照的研究，但在懷孕期間，這種藥物可以在確實需要時使用。
與您的醫生討論並告訴他們有關該藥物的意見。
目前還沒有關於這種藥物是否透過母乳傳染給嬰兒的具體資訊。 哺乳前請與您的醫師討論。
Pack Size & Price
50's pack Price : ৳250
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