Precautions and warnings

Silver sulfadiazine cream should be used carefully if you have serious liver or kidney problems, or if you might have porphyria. People who are allergic to sulphonamides, have glucose-6-phosphate dehydrogenase (G6PD) deficiency, or are using proteolytic enzyme creams should also use this cream with caution. Silver sulfadiazine cream can slow down the healing process by delaying the removal of dead skin from burns and may change how burns look.

Drug Interactions

Enhances the blood sugar-lowering effect of sulfonylureas. Its action is not blocked by PABA.

Contraindications

Silver sulfadiazine cream should not be used by people who are allergic to silver sulfadiazine, sulfonamides, or any ingredients in the cream, like cetyl alcohol or propylene glycol. Because sulfonamides can raise the risk of a serious brain condition called kernicterus, this cream should not be used on pregnant women close to their due date, premature babies, or infants under a few months old. Do not use this cream if you have liver or kidney problems, or if you might have a condition called porphyria.

Mode of actions

Silver sulfadiazine works against many types of germs, including both gram-positive and gram-negative bacteria, as well as some yeasts and fungi. The silver in the medicine mainly attacks the cell wall and membrane of these germs, breaking them down. This damage stops important enzymes and the DNA and RNA of the bacteria from working, which eventually kills the cell.

Dosage & Administration

Adult: Topical As 1% cream: Apply onto affected area 1-2 times/day.

Burns: The burn wound should be cleaned and cream applied over all the affected areas to a depth of 3-5mm. Where necessary, the cream should be re-applied to any area from which it has been removed by patient activity. In burns, cream should be re-applied at least every 24 hours or more frequently if the volume of exudate is large.

Hand burns: Before application of Sibalyn® cream to the burn, the whole hand should be enclosed in a clear plastic bag or glove . The patient should be encouraged to move the hand and fingers. The dressing should be changed when an excessive amount of exudate has accumulated in the bag.

Leg Ulcers/Pressure Sores: The cavity of the ulcer should be filled with Cream to a depth of at least 3-5mm. As Cream can cause maceration of normal skin on prolonged contact, care should be taken to prevent spread onto non-ulcerated areas. Application of Cream should be followed by an absorbent pad or gauze dressing, with further application of pressure bandaging as appropriate for the ulcer.The dressings should normally be changed daily but for wounds which are less exudative, less frequent changes (every 48 hours) may be acceptable.

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.

Discuss with your doctors and tell them feedback about this medicine.

There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.

Pack Size & Price