Fengel 1% (Gel)
Manufactured by: Pharmadesh Laboratories Ltd.
Diclofenac Sodium 1% Topical Similar medicine
Fengel 1% is indicated for
- Rheumatoid arthritis
- Osteoarthritis
- Joint
- muscular pains
Precautions and warnings
Peptic ulcers or gastrointestinal bleeding can rarely happen in people using Diclofenac. Older patients should be watched carefully. The gel should not touch your eyes or the inside of your mouth or nose. After putting on the gel, wash your hands well, and do not swallow it.
Side-effects
- Generally well tolerated. Adverse effects are mild
- rare
- transient. At the starting of the treatment
- however
- patients may be sometimes complaining of epigastric pain
- eructation
- nausea
- diarrhea or dizziness or headache. These effects are usually mild in nature. Peripheral edema
- skin reactions
- such as rash
- eczema have also been encountered. Gel may cause local irritation
- reddening of the skin
- skin rash.
Drug Interactions
- Diclofenac may raise the levels of methotrexate in your blood.
- Taking diclofenac with other NSAIDs or blood thinners (such as warfarin) increases the risk of stomach or gut bleeding.
- Using it together with ciclosporin or triamterene can increase the risk of kidney problems.
- If you already have serious corneal inflammation, using diclofenac eye drops along with steroid eye drops may raise the chance of corneal issues.
- Colestyramine and colestipol can lower the amount of diclofenac your body absorbs.
- Taking sucralfate before diclofenac can decrease diclofenac’s blood levels.
- Diclofenac eye drops may make acetylcholine and carbachol eye medicines less effective.
- Diclofenac may increase the levels of lithium and digoxin in your blood.
Contraindications
This product should not be used by people who are allergic to any of its ingredients. It is also not suitable for those with peptic ulcers or allergies to diclofenac, similar drugs, or other non-steroidal anti-inflammatory drugs (NSAIDs). Diclofenac should not be used by asthma patients whose attacks are triggered by aspirin or other drugs that inhibit prostaglandin production. Additionally, do not apply the gel under bandages or airtight dressings.
Mode of actions
Diclofenac is a common NSAID (non-steroidal anti-inflammatory drug) belonging to the phenylacetic acid group. It strongly reduces inflammation, relieves pain, and lowers fever. Diclofenac works by blocking the enzymes COX-1 and COX-2, which are needed to make prostaglandins, substances that cause inflammation and pain. It may also help by reducing the activity of certain immune cells (neutrophils and lymphocytes), lowering inflammation-related chemicals (cytokines), and decreasing the movement of inflammatory cells to injury sites.
Dosage & Administration
Gel: For external use only. Depending on the size of area to be treated, 2-4 g of Gel should be applied to the skin 3-4 times daily. To the affected area gel should be rubbed in lightly.
Gel may also be given in addition to further treatment with other dosage forms of Diclofenac.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
15gm tube Price : ৳19.68
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