Didryl 10mg/5ml (Syrup)
Manufactured by: G. A. Company Ltd.
Diphenhydramine Hydrochloride Similar medicine
Didryl is indicated for
- Rinitis alergi
- Kondisi alergi
- Mabuk perjalanan
- Pilek
- Insomnia
- Gejala ekstrapiramidal
Precautions and warnings
Berhati-hatilah pada penderita epilepsi, lansia, dan mereka yang melakukan tugas yang memerlukan kewaspadaan mental. Berhati-hatilah juga pada kondisi seperti glaukoma sudut tertutup, penyumbatan pada lambung atau usus, penyumbatan saluran kemih, tiroid yang terlalu aktif (hipertiroidisme), peningkatan tekanan di dalam mata, penyakit jantung, asma parah, dan selama kehamilan.
Side-effects
- Depresi SSP
- pusing
- sakit kepala
- sedasi; stimulasi paradoks pada anak; mulut kering
- sekresi pernafasan menebal
- penglihatan kabur
- retensi urin; gangguan GI; diskrasia darah.
Drug Interactions
Menutupi efek berbahaya pada telinga (ototoksisitas) yang disebabkan oleh antibiotik aminoglikosida. Menjadikan levodopa kurang efektif dengan memecahnya lebih cepat di lambung dan memperlambat penyerapannya dengan menunda pengosongan lambung. Mengurangi efektivitas obat kolinergik, seperti tacrine dan Donepezil, serta antipsikotik tertentu. Suplemen herbal seperti valerian, St. John’s wort, Kava Kava, dan pegagan dapat meningkatkan rasa kantuk atau sedasi.
**Bahaya:**
Mencampur dengan alkohol, barbiturat, obat penghilang rasa sakit, obat tidur, dan antipsikotik dapat meningkatkan rasa kantuk atau depresi pada sistem saraf pusat secara berbahaya. Ketika dikonsumsi dengan MAOI, atropin, atau antidepresan trisiklik (TCA), obat ini juga dapat meningkatkan efek samping antimuskarinik.
Contraindications
Hipersensitivitas; neonatus, laktasi.
Mode of actions
Diphenhydramine bekerja dengan cara memblokir reseptor histamin H1 yang terdapat di sistem pencernaan, pembuluh darah, dan saluran udara. Ini dapat membuat Anda mengantuk dan juga memiliki beberapa efek yang mirip dengan obat yang memblokir asetilkolin (efek antikolinergik).
Dosage & Administration
Lisan
Dewasa: Sebagai hidroklorida: 25-50 mg 3-4 kali sehari. Maks: 300 mg/hari.
Anak: 6,25-25 mg 3-4 kali sehari, hingga 5 mg/kg dalam dosis terbagi. Maks: 300 mg/hari.
Pengobatan dan pencegahan mabuk perjalanan
Dewasa: Sebagai diphenhydramine di (acefyllinate): Dosis biasa: 90-135 mg, dapat diulang jika diperlukan dengan interval minimal 6 jam. Maks: 540 mg setiap hari. Untuk pencegahan, dosis diberikan minimal 30 menit sebelum bepergian.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan telah menunjukkan efek buruk bahkan terkadang tidak dapat menunjukkan risiko pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan hanya jika benar-benar diperlukan.
Diskusikan dengan dokter Anda dan beri tahu mereka tanggapan tentang obat ini.
Belum ada informasi spesifik apakah obat ini ditularkan ke bayi melalui ASI. Diskusikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
100ml bot Price : ৳30
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