Integril 2 20mg/10ml (Injection)
Manufactured by: Incepta Pharmaceuticals Ltd.
Eptifibatide Similar medicine
Integril 2 is indicated for
- Myocardial infarction
- Unstable angina
- Angioplasty
- Percutaneous coronary intervention (PCI)
Precautions and warnings
Stop use if there is serious bleeding that cannot be controlled, or if the patient needs emergency surgery or thrombolytic treatment. Also, consider liver problems and check platelet counts.
Side-effects
- Bleeding
- hypotension; localised Injection site reaction; thrombocytopaenia; back pain; anaphylaxis; GI
- intracranial or pulmonary haemorrhage.
Drug Interactions
Using heparin with other blood thinners, antiplatelet drugs, or clot-busting medicines increases the risk of bleeding.
Contraindications
Active bleeding, a higher risk of bleeding (including bleeding disorders), brain blood vessel problems, a history of stroke, uncontrolled high blood pressure, serious injuries, severe kidney problems, or having had major surgery recently. Not recommended during breastfeeding.
Mode of actions
Eptifibatide is a small, ring-shaped protein made of seven amino acids. It works by blocking a specific receptor on platelets called glycoprotein IIb/IIIa. This prevents platelets from clumping together, which helps reduce the risk of blood clots forming.
Dosage & Administration
Adult: IV:
Acute Coronary Syndrome
• In patients with normal renal function: The recommended adult dosage is an IV bolus of 180 mcg/kg as soon as possible following diagnosis, followed by a continuous infusion of 2.0 mcg/kg/min until hospital discharge or initiation of CABG surgery, up to 72 hours. If a patient is to undergo a PCI the infusion should be continued up to hospital discharge, or for up to 18 to 24 hours after the procedure, whichever comes first, allowing for up to 96 hours of therapy.
• In patients with creatinine clearance
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.
Discuss with your doctors and tell them feedback about this medicine.
There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.
Pack Size & Price
10ml vial Price : ৳3000
Similar medicine
Manufactured by: Incepta Pharmaceuticals Ltd.
Manufactured by: Incepta Pharmaceuticals Ltd.
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There are few similar medicines of Integril 2 are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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