Naprosyn Plus 500/20mg (Tablet)
Manufactured by: Radiant Pharmaceutical Ltd.
Esomeprazole + Naproxen Similar medicine
Naprosyn Plus 500/20mg is indicated for
- Rheumatoid arthritis
- Osteoarthritis
- Ankylosing spondylitis
- Joint stiffness
Precautions and warnings
Tell your doctor if you have ever had asthma, liver disease, bleeding, ulcers, recurring heartburn, heart disease such as a history of heart attack, high blood pressure, stroke, edema, fluid retention, low sodium blood levels, blood disorders such as anemia, bleeding or clotting problems, nasal polyps, or lupus before taking this medication.
NSAID drugs, such as naproxen, can cause kidney difficulties in certain people. If you're dehydrated, have heart failure or kidney illness, are an older adult or take certain medications, you're more likely to have problems. To avoid dehydration, drink plenty of fluids as advised by your doctor, and report any changes in the amount of urine to your doctor right away.
This medication may cause dizziness or drowsiness. You may become dizzy or sleepy if you consume alcohol or cannabis. Do not drive, operate machinery, or engage in any other activity that requires attentiveness until you are sure you can do so safely. Limit your intake of alcoholic beverages. If you use cannabis, talk to your doctor.
This medicine has the potential to induce stomach bleeding. The use of alcohol and tobacco on a regular basis, especially in combination with this prescription, may raise the risk of stomach bleeding. For more information, talk to your doctor or pharmacist.
Side-effects
- In general
- The most common adverse reactions in clinical trials (>5%): erosive gastritis
- dyspepsia
- gastritis
- diarrhea
- gastric ulcer
- upper abdominal pain
- nausea etc.
Drug Interactions
Aliskiren, ACE inhibitors such as captopril and lisinopril, angiotensin II receptor blockers such as valsartan and losartan, corticosteroids such as prednisone, lithium, methotrexate, especially high-dose therapy, and rifampin are some of the products that may interact with this medicine.
When combined with other drugs that can cause bleeding, this medication can increase the risk of bleeding. Antiplatelet medications like clopidogrel, as well as "blood thinners" like dabigatran/enoxaparin/warfarin, are examples.
Some products require stomach acid to be adequately absorbed by the body. Because esomeprazole reduces stomach acid, it may affect how effectively these medications perform. Atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirine, and certain azole antifungals like itraconazole, ketoconazole, and posaconazole are among the products affected.
Contraindications
• Hypersensitivity to any of Progesic's ingredients or substituted benzimidazoles.
• Asthma, urticaria, or other allergic responses after using aspirin or other nonsteroidal anti-inflammatory drugs
• In the case of coronary artery bypass graft (CABG) surgery, use during the peri-operative period.
• A lady who is late in her pregnancy.
Mode of actions
A prototypical NSAID is a naproxen, a propionic acid derivative. It inhibits the cyclooxygenase-1 and -2 (COX-1 and -2) enzymes in a reversible manner, resulting in a reduction in prostaglandin precursor synthesis. It possesses anti-inflammatory, analgesic, and antipyretic properties, as well as inhibiting platelet aggregation.
Esomeprazole is a proton pump inhibitor (PPI) that inhibits H+/K+ ATPase in the gastric parietal cell, suppressing gastric acid output. It's the omeprazole S-isomer.
Dosage & Administration
Rheumatoid Arthritis, Osteoarthritis, Alkylosing Spondylitis, and dysmenorrhoea: 375 or 500 mg, one tablet twice daily.
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
24's pack Price : ৳480
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