Precautions and warnings

Cholestatic jaundice and fat-malabsorption conditions: Monitor patients carefully for signs of toxicity, especially those with liver problems and children.

Drug Interactions

Neomycin can lower the absorption of this medicine. Taking synthetic retinoids (such as acitretin, isotretinoin, or tretinoin) increases the risk of having too much vitamin A in your body. Using this medicine with alcohol can also increase the risk of side effects or toxicity.

Contraindications

Hypervitaminosis A; pregnancy (dose exceeding RDA).

Mode of actions

Vitamin A is important for the proper function of the retina in the eye and is necessary for the growth and development of skin and other body tissues.

Dosage & Administration

Adult: PO Vitamin A deficiency For severe deficiency w/ corneal changes: 500,000 u/day for 3 days, followed by 50,000 u/day for 2 wk and then 10,000-20,000 u/day for 2 mth as follow-up therapy.

For cases w/o corneal changes: 10,000-25,000 u/day until clinical improvement occurs (usually 1-2 wk).

Pregnancy & Lactation

Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy and there is not enough evidence of risk in later trimesters.

Pack Size & Price