Pylotrip (Kit)
Manufactured by: Square Pharmaceuticals Ltd.
Amoxicillin + Clarithromycin + Lansoprazole Kit Similar medicine
Pylotrip is indicated for
- 幽門螺旋桿菌感染、消化性潰瘍病
Precautions and warnings
服用青黴素（尤其是阿莫西林）的患者會出現嚴重甚至有時致命的超敏反應（過敏性反應）。 過敏反應在腸外用藥後較常見，但也發生在服用口服青黴素的人身上。 有青黴素過敏史和/或多種過敏原敏感性的個體更容易出現這些反應。
Side-effects
- 據報告可能或很可能與治療有關的不良反應（
Drug Interactions
阿莫西林：阿莫西林可能會損害 OC 的有效性。 抗凝血作用可能會放大。 別嘌呤醇會增加過敏反應的風險。 丙磺舒會導致血液濃度升高和延長。 氯黴素、大環內酯類、磺胺類和四環素藥物都會幹擾阿莫西林的殺菌作用。
克拉黴素：同時服用克拉黴素和 CYP3A4 受質的人已記錄到嚴重的副作用。 秋水仙鹼毒性；辛伐他汀、洛伐他汀和阿托伐他汀治療橫紋肌溶解症； CYP3A4 代謝的鈣通道阻斷劑導致低血壓和急性腎損傷； CYP3A4 代謝的鈣通道阻斷劑（例如維拉帕米、氨氯地平、地爾硫卓、硝苯地平）導致低血壓和嚴重腎損傷。 大多數與 CYP3A4 代謝的鈣通道阻斷劑相關的急性腎損傷病例涉及 65 歲及以上的老年患者。
蘭索拉唑與利尿劑和地高辛一起，會增加低鎂血症的風險。 厄洛替尼、達沙替尼和拉帕替尼的血漿濃度可能會降低。 伊曲康唑和酮康唑的生物利用度可能會降低。 西洛他唑和甲胺蝶呤的血漿濃度可能會增加。 抗酸劑和硫糖鋁都會降低生物利用度。
利匹韋林和阿扎那韋的血清水平和藥理作用可能會降低，這可能是致命的。
Contraindications
對於對任何成分有極度過敏史的患者，不建議使用。 不建議因先前使用克拉黴素而出現膽汁淤積性黃疸或肝功能障礙的患者使用克拉黴素。 有 QT 間期延長或室性心律不整（尤其是尖端扭轉型室性心搏過速）病史的患者不應使用克拉黴素。
對阿莫西林或其他 β-內醯胺抗生素（如青黴素和頭孢菌素）有嚴重過敏反應史（如過敏反應或史蒂文斯-約翰遜症候群）是禁忌症。
已知對克拉黴素、紅黴素或任何大環內酯類抗生素過敏的患者應避免服用克拉黴素。
不建議因先前使用克拉黴素而出現膽汁淤積性黃疸或肝功能障礙的患者使用克拉黴素。
有 QT 間期延長或室性心律不整（尤其是尖端扭轉型室性心搏過速）病史的患者不應使用克拉黴素。
對於 CrCl 低於 30 mL/min 的患者，不適用阿莫西林/克拉黴素/蘭索拉唑。
Mode of actions
質子幫浦抑制劑蘭索拉唑與胃壁細胞中的 H+/K+ 交換 ATP 酶（質子幫浦）結合，防止胃酸產生。
阿莫西林透過與一種或多種青黴素結合蛋白結合，阻斷細胞壁生物合成中肽聚醣產生的最後轉肽階段。
克拉黴素是一種抗生素，透過附著在 50S 核醣體亞基上抑制蛋白質合成。
Dosage & Administration
每天兩次，每次 1 次，持續 7-14 天，或依照醫師的建議。
Pregnancy & Lactation
雖然動物生殖研究顯示出不良影響，甚至有時無法證明對胎兒的風險，並且在孕婦中沒有充分和良好對照的研究，但在懷孕期間，這種藥物可以在確實需要時使用。
與您的醫生討論並告訴他們有關該藥物的意見。
Pack Size & Price
7's pack Price : ৳386.46
Similar medicine
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