Cinalid 500mg (Tablet)
Manufactured by: Jayson Pharmaceuticals Ltd.
Azithromycin Similar medicine
Cinalid is indicated for
- Bacterial infections
- bacterial endocarditis
- typhoid fever
- community-acquired pneumonia
- uncomplicated gonorrhea
- streptococcal pharyngitis/tonsillitis
- COPD
- acute bacterial sinusitis
- acute otitis media
- uncomplicated UTI
- Uncomplicated gonorrhea
- PID
- non-gonococcal urethritis
- chancroid
- acute salmonellosis
- cervicitis
- babesiosis
- chlamydial infections
- pelvic inflammatory disease
- PID
- traveler's diarrhea
Precautions and warnings
Prolonged QT interval, low K or Mg blood levels, slow heart rate, and medicine treating irregular heart rhythms may all raise the risk of Torsades de pointes and fatal heart arrhythmias in patients. Hepatic and renal function are both impaired. Lactation and pregnancy. Parameters to be monitored Liver function tests, CBC, and differential are all recommended.
Side-effects
- GI disturbances
- visual impairment
- irritation; deafness
- dizziness
- headache
- fatigue
- anorexia
- paraesthesia
- dysgeusia
- nasal congestion
- sinusitis
- facial swelling
- periocular swelling
- pruritus
- rash
- urticaria
- arthralgia
- vaginitis; inj site pain
- inflammation; decreased lymphocyte count
- blood bicarbonate
- increased eosinophil count
- transaminase levels and/or alkaline phosphatase levels. Potentially Fatal: Angioedema
- cholestatic jaundice.
Drug Interactions
Digoxin, ciclosporin, terfenadine, hexobarbital, and phenytoin serum concentrations are also increased. Antacids containing aluminum and magnesium reduce the rate of absorption. Ergot poisoning is more likely.
Pimozide increases the risk of cardiotoxicity, which can be fatal.
Contraindications
Azithromycin, erythromycin, or any macrolide or ketolide antibiotic have been known to cause hypersensitivity. Along with pimozide, coadministration is recommended. Prior usage of azithromycin has been linked to cholestatic jaundice and hepatic impairment.
Mode of actions
Azithromycin is an azalide antibiotic that is semisynthetic. It disrupts RNA-dependent protein synthesis at the chain elongation step by attaching to the 50s ribosomal subunit of sensitive organisms and blocking transpeptidation.
Dosage & Administration
Adult: PO Resp tract infections; Skin and soft tissue infections 500 mg once daily for 3 days. Chancroid; Non-gonococcal cervicitis/urethritis due to Chlamydia trachomatis; Uncomplicated genital infections due to Chlamydia trachomatis 1 g as a single dose.
Prophylaxis of disseminated MAC infections 1.2 g once wkly. Treatment or secondary propjhylaxis: 500 mg once daily w/ other antimycobacterials.
Uncomplicated gonorrhoea 2 g as a single dose. Granuloma inguinale Initial: 1 g, then 500 mg/day until all lesions have healed completely.
Active immunisation against typhoid fever caused by Salmonella typhi 1 g once daily for 5 days.
IV Community-acquired pneumonia 500 mg as a single IV daily dose for 2 days, then 500 mg single oral dose daily to complete 7-10 days of therapy.
Pelvic inflammatory disease 500 mg as a single IV daily dose for 1-2 days, then 250 mg single oral dose daily to complete a 7-day therapy.
Child: >6 mth 10 mg/kg; 15-25 kg: 200 mg; 26-35 kg: 300 mg; 36-45 kg: 400 mg. All doses to be taken once daily for 3 days.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.
Discuss with your doctors and tell them feedback about this medicine.
There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.
Pack Size & Price
3's pack Price : ৳75.3
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