Azonam 1gm/vial (Injection)
Manufactured by: Incepta Pharmaceuticals Ltd.
Aztreonam Similar medicine
Azonam is indicated for
- सिस्टिक फाइब्रोसिस
- पेरिटोनिटिस
- जीवाणु संक्रमण
- यूटीआई
- निचले श्वसन पथ के संक्रमण
- सिस्टिटिस
- गोनोरिया
- सेप्टीसीमिया
- त्वचा और त्वचा-संरचना संक्रमण
- एंडोमेट्रैटिस
- पेल्विक सेल्युलाइटिस
Precautions and warnings
अन्य बीटा-लैक्टम, गुर्दे, गर्भवती महिलाओं और यकृत हानि के प्रति अतिसंवेदनशीलता।
Side-effects
- IV: फ़्लोएबिटिस और थ्रोम्बोफ्लोएबिटिस। आईएम: चोट वाली जगह पर दर्द और सूजन; दस्त
- मतली
- उल्टी
- बदला हुआ स्वाद; पीलिया
- हेपेटाइटिस
- उच्च यकृत एंजाइम; लंबा प्रोथ्रोम्बिन समय
- आंशिक थ्रोम्बोप्लास्टिन समय; दाने
- पित्ती
- ईोसिनोफिलिया। संभावित रूप से घातक: थ्रोम्बोसाइटोपेनिया
- न्यूट्रोपेनिया; अतिसंवेदनशील जीवों की अतिवृद्धि; स्यूडोमेम्ब्रेनस कोलाइटिस.
Drug Interactions
मौखिक एंटीकोआगुलंट्स के साथ समवर्ती उपयोग से प्रोथ्रोम्बिन समय बढ़ सकता है।
Contraindications
स्तनपान की अतिसंवेदनशीलता.
Mode of actions
एज़ट्रोनम में ग्राम-नेगेटिव बैक्टीरिया के पेनिसिलिन-बाइंडिंग प्रोटीन 3 (पीबीपी-3) के प्रति उच्च आकर्षण है और इसलिए यह बैक्टीरिया कोशिका दीवार के निर्माण को अवरुद्ध करके जीवाणुनाशक प्रभाव डालता है। यह लैक्टामेज़ हाइड्रोलिसिस के प्रति बहुत प्रतिरोधी है। एंटरोबैक्टीरियासी एसपीपी, ई. कोली, क्लेबसिएला, प्रोटियस, प्रोविडेंसिया, साल्मोनेला, सेराटिया, शिगेला और येर्सिनिया एसपीपी सभी अतिसंवेदनशील हैं।
Dosage & Administration
वयस्क: IV/IM Gm-ve संक्रमण गंभीरता के आधार पर विभाजित खुराक में 1-8 ग्राम/दिन। अधिकतम: 8 ग्राम/दिन।
यूटीआई 0.5-1 ग्राम 8-12 घंटे।
आईएम सिस्टिटिस; सूजाक 1 ग्राम एक खुराक के रूप में।
बच्चे: और शिशु >1 सप्ताह: हर 6 या 8 घंटे में 30 मिलीग्राम/किग्रा; >2 वर्ष: गंभीर संक्रमण के लिए हर 6 या 8 घंटे में 50 मिलीग्राम/किग्रा। खुराक गहरी आईएम इंजे या धीमी IV इंजे या जलसेक के माध्यम से दी जा सकती है। 1 ग्राम से अधिक खुराक IV मार्ग से दी जानी चाहिए। अधिकतम (>2 वर्ष): 8 ग्राम/दिन।
गुर्दे की हानि: मध्यम से गंभीर हानि: प्रारंभिक खुराक समान, रोगी के सीआरसीएल के अनुसार रखरखाव खुराक समायोजित करें। हेमोडायलिसिस: प्रत्येक सत्र के बाद प्रारंभिक खुराक की 1/8 की पूरक खुराक दी जा सकती है।
सीआरसीएल (एमएल/मिनट)
10-30 रखरखाव खुराक: प्रारंभिक खुराक का आधा।
Pregnancy & Lactation
यद्यपि पशु प्रजनन अध्ययनों ने प्रतिकूल प्रभाव दिखाया है, यहां तक कि कभी-कभी भ्रूण पर जोखिम प्रदर्शित करने में असमर्थ होते हैं और गर्भवती महिलाओं में पर्याप्त और अच्छी तरह से नियंत्रित अध्ययन नहीं होते हैं, लेकिन गर्भावस्था के दौरान, इस दवा का उपयोग केवल तभी किया जा सकता है जब निश्चित रूप से आवश्यकता हो।
अपने डॉक्टरों से चर्चा करें और उन्हें इस दवा के बारे में फीडबैक बताएं।
इस बारे में कोई विशेष जानकारी नहीं है कि यह दवा स्तन के दूध के माध्यम से बच्चे तक पहुंचती है या नहीं। स्तनपान कराने से पहले अपने डॉक्टर से चर्चा करें।
Pack Size & Price
1's pack Price : ৳400
Similar medicine
Manufactured by: Incepta Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
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